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Lancet Oncol:乳腺导管原位癌的筛查治疗对于预防浸润性乳腺癌是值得的!

2015-12-05 MedSci MedSci原创

乳腺导管原位癌(ductal carcinoma in situ, DCIS)的筛查检测和治疗的价值目前仍然是有争议的。目前,DCIS的诊断和治疗对于预防浸润性乳腺癌的发生的效果仍不明确。因此有必要研究清楚DCIS的筛查检测和随后与筛查相关的间隔浸润性乳腺癌的发病的关系。研究人员从英格兰、威尔士和北爱尔兰的11个地区的84家当地筛查单位获得了乳腺癌筛查检测的数据。数据由国家卫生健康服务乳腺筛查计划

乳腺导管原位癌(ductal carcinoma in situ, DCIS)的筛查检测和治疗的价值目前仍然是有争议的。目前,DCIS的诊断和治疗对于预防浸润性乳腺癌的发生的效果仍不明确。因此有必要研究清楚DCIS的筛查检测和随后与筛查相关的间隔浸润性乳腺癌的发病的关系。


研究人员从英格兰、威尔士和北爱尔兰的11个地区的84家当地筛查单位获得了乳腺癌筛查检测的数据。数据由国家卫生健康服务乳腺筛查计划提供。DCIS诊断的数据来自于与年龄在50-64岁的女性。她们均在2004年4月1日至2007年3月31日间接受了乳房X光影像筛查。DCIS检测频率作为一个持续性的和分类的变量。

研究人员共分析了5243658名女性的数据,以及在相关筛查后36个月的癌症发病情况。DCIS检测的评价频率为每1000名筛查的女性中有1.60人。筛查检测的DCIS病例和间隔浸润性乳腺癌发病率呈显著的负相关。90%的单位的DCIS检测频率在每1000名女性中位1.00-2.22人的范围内。在这些单位中,对于筛查检测的DCIS病例,在接下来的三年中,低于三分之一的人患上了浸润性乳腺癌。

此项研究揭示了筛查检测的DCIS和随后发生的间隔浸润性乳腺癌之间的联系。这表明DCIS的检测和治疗对于将来预防浸润性乳腺癌的发生有着重要的价值。

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    2016-06-07 minlingfeng
  2. [GetPortalCommentsPageByObjectIdResponse(id=1864746, encodeId=39e91864e46e9, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Tue Jun 07 22:27:00 CST 2016, time=2016-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1744889, encodeId=56631e4488961, content=<a href='/topic/show?id=af1b3e01076' target=_blank style='color:#2F92EE;'>#原位癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37010, encryptionId=af1b3e01076, topicName=原位癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7b5435458088, createdName=july_987, createdTime=Sat Oct 29 03:27:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828340, encodeId=40011828340b4, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue May 03 08:27:00 CST 2016, time=2016-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48889, encodeId=95be4888908, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:28:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45541, encodeId=fef8455418c, content=乳腺导管原位癌(ductalcarcinomainsitu,DCIS), beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Dec 11 12:58:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461258, encodeId=341f146125869, content=<a href='/topic/show?id=4ebd65e084e' target=_blank style='color:#2F92EE;'>#浸润性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65708, encryptionId=4ebd65e084e, topicName=浸润性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91ec6409669, createdName=xuyu, createdTime=Mon Dec 07 06:27:00 CST 2015, time=2015-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488916, encodeId=a637148891628, content=<a href='/topic/show?id=17d023e08fc' target=_blank style='color:#2F92EE;'>#乳腺导管原位癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23708, encryptionId=17d023e08fc, topicName=乳腺导管原位癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd328483932, createdName=daviiliu, createdTime=Mon Dec 07 06:27:00 CST 2015, time=2015-12-07, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1864746, encodeId=39e91864e46e9, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Tue Jun 07 22:27:00 CST 2016, time=2016-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1744889, encodeId=56631e4488961, content=<a href='/topic/show?id=af1b3e01076' target=_blank style='color:#2F92EE;'>#原位癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37010, encryptionId=af1b3e01076, topicName=原位癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7b5435458088, createdName=july_987, createdTime=Sat Oct 29 03:27:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828340, encodeId=40011828340b4, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue May 03 08:27:00 CST 2016, time=2016-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48889, encodeId=95be4888908, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:28:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45541, encodeId=fef8455418c, content=乳腺导管原位癌(ductalcarcinomainsitu,DCIS), beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Dec 11 12:58:00 CST 2015, time=2015-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461258, encodeId=341f146125869, content=<a href='/topic/show?id=4ebd65e084e' target=_blank style='color:#2F92EE;'>#浸润性乳腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65708, encryptionId=4ebd65e084e, topicName=浸润性乳腺癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91ec6409669, createdName=xuyu, createdTime=Mon Dec 07 06:27:00 CST 2015, time=2015-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488916, encodeId=a637148891628, content=<a href='/topic/show?id=17d023e08fc' target=_blank style='color:#2F92EE;'>#乳腺导管原位癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23708, encryptionId=17d023e08fc, topicName=乳腺导管原位癌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd328483932, createdName=daviiliu, createdTime=Mon Dec 07 06:27:00 CST 2015, time=2015-12-07, status=1, ipAttribution=)]
    2016-05-03 howi
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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

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    2015-12-11 jetleo

    乳腺导管原位癌(ductalcarcinomainsitu,DCIS)

    0

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