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JAHA:使用立体定位放射外科手术进行猪房室结消融:心律失常无导管消融的可行性研究

2017-10-30 xiangting MedSci原创

无导管放射消融—使用基于直线加速器的立体定位放射外科手术在完整的猪模型中是可行的。

可以传导到心律失常病灶基于直线加速器的立体定位放射外科手术是一种有前景的无导管消融模式。研究人员使用立体定位放射外科手术测试了在猪体内进行房室(AV)节消融的可行性。

共研究了 5只大白品种猪(重量40-75kg; 4只为雌性)。每只猪均植入了单室St Jude起搏器。将猪进行全身麻醉后,进行冠脉/心脏计算机断层模拟扫描以定位AV节。锥束CT扫描用于目标定位。立体定位放射外科手术剂量范围为35至40 Gy,通过直线加速器递送至AV节,并对猪每周进行起搏器检查以观察潜在的心电图变化。一旦观察到变化,即将猪进行安乐死,并将各种组织的病理标本,包括AV结和AV节周围的组织用来研究辐射的影响。5只猪都有AV传导障碍,并逐渐转变为完全心脏阻滞。宏观检查显示没有心肌损伤,猪在超声心动图上保留了收缩功能。免疫染色显示AV结的目标区域有纤维化,而非目标区域没有检测到纤维化。

无导管放射消融-使用基于直线加速器的立体定位放射外科手术在完整的猪模型中是可行的。

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    2017-11-01 zhaohui6731
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    2017-11-01 muzishouyi
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    2017-10-30 131****1460

    学习了受益匪浅

    0

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医学研究表明,轻度的鼾声对人体健康影响不大,引起医学界关注的鼾症是睡眠中伴有呼吸暂停的鼾症,可导致不同程度缺氧,时间久了,会引起人体内激素分泌功能紊乱,从而造成多种系统、组织器官的损害;引起大脑、血液严重缺氧,形成低氧血症,对心血管系统损害甚大,可引起高血压、冠心病等,严重者可致夜间猝死。儿童鼾症则会影响身体与智力发育。

GW-ICC2017︱唐闽:肿瘤相关室性心律失常的导管消融治疗

肿瘤及心血管疾病均是我国居民的主要死因,心脏肿瘤合并心律失常使临床诊治变得错综复杂。在本届长城国际心脏病学会议(GW-ICC 2017),来自中国医学科学院阜外心血管病医院的唐闽教授团队发表《肿瘤相关的室性心律失常导管消融治疗》的精彩学术报告,引发了参会专家学者对肿瘤心脏病学这门新兴学科的深刻思考。

GW-ICC2017︱全面解读心律失常治疗之创新

心律失常作为心血管领域的常见病及心源性猝死的主要原因之一,其多样性、复杂性及隐匿性常给临床诊治带来不小的难度。近年来,诊疗水平的不断进步使得治疗手段的选择和应用都更加合理化和个体化,日新月异的发展势头也对临床工作者提出更高要求。在本届GW-ICC 2017的美国华裔心脏协会(CNAHA)@GW-ICC联合论坛上,来自斯坦福大学的Paul J Wang教授就这一热点问题作了精彩的专场解析。下面带您一

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