Baidu
map

Circulation:经血管内超声肾交感神经去神经化治疗(RDN)后6个月的降压效果

2019-06-04 QQ MedSci原创

RADIANCE-HTN SOLO试验显示,在未服用抗高血压药物的患者中,通过血管内超声进行肾交感神经去神经化治疗(RDN)后2个月,白天收缩压降低6.3mmHg以上。现对该试验的后续结果进行汇报。停用抗高血压药物(至多2种)4周后日间非卧床血压(BP)≥135/85 mm?Hg、<170/105 mm?Hg的患者被机分至RDN组(74人)或虚假处理组(72人)。在随访的前2个月,患者停用抗

RADIANCE-HTN SOLO试验显示,在未服用抗高血压药物的患者中,通过血管内超声进行肾交感神经去神经化治疗(RDN)后2个月,日间收缩压降低6.3mmHg以上。现对该试验的后续结果进行汇报。

停用抗高血压药物(至多2种)4周后日间非卧床血压(BP)≥135/85 mm?Hg、<170/105 mm?Hg的患者被机分至RDN组(74人)或虚假处理组(72人)。在随访的前2个月,患者停用抗高血压药物,除非超过安全BP标准。从第2个月到第5个月,如果每月测量的在家BP≥135/85 mm?Hg,则予以标准的逐步降压治疗,包括依次添加氨氯地平(5mg/d)、标准剂量的血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂和氢氯噻嗪(12.5mg/d),然后予以静滴氢氯噻嗪(25mg/d)和氨氯地平(10mg/d)。预后结点包括6个月时日间非卧床收缩压和基础收缩压的变化以及医疗负担和安全性。

RDN组和虚假处理组分别有69位和71位患者完成6个月的血压监测。6个月时,RDN组和虚假处理组分别有65.2%和84.5%的患者采用标准的抗高血压治疗(p=0.008),RDN组抗高血压药物的平均数量和剂量均低于虚假处理组(0.9±0.9 vs 1.3±0.9,p=0.010和1.4±1.5 vs 2.0±1.8,p=0.018)。虽然RDN组强化标准抗高血压治疗的强度较低,但其日间非卧床收缩压的降低效果要优于虚假处理组(-18.1±12.2 vs -15.6±13.2 mmHg;差值 -4.3mmHg,95% CI -7.9至-0.6,p=0.024)。无严重副反应。

经血管内超声RDN的降压效果可维持至6个月,并可减少抗高血压药物的使用。

原始出处:

本文系梅斯医学(MedSci)原创编译,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
    2019-06-06 xsm922
  6. [GetPortalCommentsPageByObjectIdResponse(id=1997542, encodeId=84b4199e542fd, content=<a href='/topic/show?id=81cf9814368' target=_blank style='color:#2F92EE;'>#降压效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98143, encryptionId=81cf9814368, topicName=降压效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Aug 12 18:50:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808858, encodeId=764018088584c, content=<a href='/topic/show?id=2d7b8245e4f' target=_blank style='color:#2F92EE;'>#肾交感神经去神经化治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82457, encryptionId=2d7b8245e4f, topicName=肾交感神经去神经化治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=279b407, createdName=shanyongle, createdTime=Sat Mar 21 04:50:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292027, encodeId=383b129202e18, content=<a href='/topic/show?id=9d32981418b' target=_blank style='color:#2F92EE;'>#降压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98141, encryptionId=9d32981418b, topicName=降压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f14236, createdName=经常头晕, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489233, encodeId=15681489233ad, content=<a href='/topic/show?id=43f13e27170' target=_blank style='color:#2F92EE;'>#去神经化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37271, encryptionId=43f13e27170, topicName=去神经化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=89ce8505766, createdName=minlingfeng, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538754, encodeId=5ef41538e5440, content=<a href='/topic/show?id=89ec1519928' target=_blank style='color:#2F92EE;'>#RDN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15199, encryptionId=89ec1519928, topicName=RDN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4e013034210, createdName=xsm922, createdTime=Thu Jun 06 06:50:00 CST 2019, time=2019-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046832, encodeId=a41e10468327f, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Tue Jun 04 18:50:00 CST 2019, time=2019-06-04, status=1, ipAttribution=)]
    2019-06-04 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

Baidu
map
Baidu
map
Baidu
map