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临床医生如何解读Meta分析论文?

2021-05-30 朱熠冰,李卫 协和医学杂志

Meta分析是翻译自英文meta-analysis,其中“Meta”一词源于古希腊文,意指将事物综合起来观察。

Meta分析是翻译自英文meta-analysis,其中“Meta”一词源于古希腊文,意指将事物综合起来观察。 Meta分析的概念最早由Light和Smoth于1971年提出,是一种对不同研究结果进行合并分析的方法[1-2]。 在医学研究中,Meta分析常用于研究结果的合并,最常见的是随机对照试验(RCT)结果的合并,该方法逐渐发展为循证医学的主要研究手段之一。 Meta分析的基本步骤: (1)明确研究问题 (2)制定检索策略 (3)筛选纳入文献 (4)提取数据信息 (5)评估研究质量和偏倚风险 (6)采用Meta分析方法合并数据报告结果[1]。 2009年的一项报告显示,每年新发表的系统综述数量在2500篇以上,其中1/3为Meta分析,此后10年的发表速度提高了近10倍 [3-5]。系统综述和Meta分析汇总医疗行为的获益与危害证据,为医疗决策提供依据。 随着循证医学的发展,通过阅读Meta分析获取前沿信息已成为临床医生必须掌握的一项重要技能[3]。但Meta分析质量良莠不齐,其结果和结论能否直接应用于临床,需进行鉴别和评估,这对读者提出了更高要求。 Meta分析文献是对Meta分

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1896848, encodeId=9f1c18968484d, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Mon Sep 27 08:49:42 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888304, encodeId=9efb188830446, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Mon Mar 14 04:49:42 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978618, encodeId=9ab39e8618a1, content=不懂mate分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d3b5179404, createdName=146f2fadm18暂无昵称, createdTime=Thu Jul 01 14:46:39 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554816, encodeId=bb2e155481690, content=<a href='/topic/show?id=550522e2957' target=_blank style='color:#2F92EE;'>#临床医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22729, encryptionId=550522e2957, topicName=临床医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=453f14553881, createdName=xiaoyeshuang, createdTime=Tue Jun 01 07:49:42 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969850, encodeId=59549698503f, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=02972000979, createdName=walking, createdTime=Mon May 31 14:06:45 CST 2021, time=2021-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969743, encodeId=d247969e435d, content=忘了好久了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6515442859, createdName=ms2000000817442249, createdTime=Mon May 31 00:27:41 CST 2021, time=2021-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969661, encodeId=f4b9969661d2, content=<a href='/topic/show?id=d55f104233bd' target=_blank style='color:#2F92EE;'>#梅斯医学科研互助群#</a>欢迎加群一起探讨学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104233, encryptionId=d55f104233bd, topicName=梅斯医学科研互助群)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210530/4dcd194e80b140debd1d7d6c161b3f13/7d140f158faa42adaa5ff6054058df7d.jpg, createdBy=216b5484325, createdName=一颗小芃友, createdTime=Sun May 30 17:23:48 CST 2021, time=2021-05-30, status=1, ipAttribution=)]
    2021-09-27 一闲
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    2022-03-14 guojianrong
  3. [GetPortalCommentsPageByObjectIdResponse(id=1896848, encodeId=9f1c18968484d, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Mon Sep 27 08:49:42 CST 2021, time=2021-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888304, encodeId=9efb188830446, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Mon Mar 14 04:49:42 CST 2022, time=2022-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=978618, encodeId=9ab39e8618a1, content=不懂mate分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d3b5179404, createdName=146f2fadm18暂无昵称, createdTime=Thu Jul 01 14:46:39 CST 2021, time=2021-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554816, encodeId=bb2e155481690, content=<a href='/topic/show?id=550522e2957' target=_blank style='color:#2F92EE;'>#临床医生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=151, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22729, encryptionId=550522e2957, topicName=临床医生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=453f14553881, createdName=xiaoyeshuang, createdTime=Tue Jun 01 07:49:42 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969850, encodeId=59549698503f, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=02972000979, createdName=walking, createdTime=Mon May 31 14:06:45 CST 2021, time=2021-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969743, encodeId=d247969e435d, content=忘了好久了, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6515442859, createdName=ms2000000817442249, createdTime=Mon May 31 00:27:41 CST 2021, time=2021-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=969661, encodeId=f4b9969661d2, content=<a href='/topic/show?id=d55f104233bd' target=_blank style='color:#2F92EE;'>#梅斯医学科研互助群#</a>欢迎加群一起探讨学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=104233, encryptionId=d55f104233bd, topicName=梅斯医学科研互助群)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210530/4dcd194e80b140debd1d7d6c161b3f13/7d140f158faa42adaa5ff6054058df7d.jpg, createdBy=216b5484325, createdName=一颗小芃友, createdTime=Sun May 30 17:23:48 CST 2021, time=2021-05-30, status=1, ipAttribution=)]
    2021-07-01 146f2fadm18暂无昵称

    不懂mate分析

    0

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    2021-05-31 walking

    学习

    0

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    2021-05-31 ms2000000817442249

    忘了好久了

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    2021-05-30 一颗小芃友

    #梅斯医学科研互助群#欢迎加群一起探讨学习

    0

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