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J Periodontol:胰岛素抵抗可用于预测牙龈/牙周炎症的风险

2018-03-11 MedSci MedSci原创

本研究旨在评估胰岛素抵抗(IR)是否可预测口腔炎症的发生风险,评估为探诊时出血部位(BOP)的数量和探诊深度(PPD)≥4mm和BOP的牙齿数目。研究人员分析了来自San Juan超重成人纵向研究的870名超重/肥胖无糖成人,年龄为40-65岁。使用稳态模型评估IR(HOMA-IR)指数评估的基线IR分为三分位数。在颊和舌侧位置评估BOP,在每个牙齿六个位点评估PPD。使用负二项回归来评估校正了基

本研究旨在评估胰岛素抵抗(IR)是否可预测口腔炎症的发生风险,评估为探诊时出血部位(BOP)的数量和探诊深度(PPD)≥4mm和BOP的牙齿数目。

研究人员分析了来自San Juan超重成人纵向研究的870名超重/肥胖无糖成人,年龄为40-65岁。使用稳态模型评估IR(HOMA-IR)指数评估的基线IR分为三分位数。在颊和舌侧位置评估BOP,在每个牙齿六个位点评估PPD。使用负二项回归来评估校正了基线年龄,性别,吸烟状况,饮酒量,受教育程度,体育锻炼,腰围,平均斑块指数和BOP部位基线数的口腔炎症风险比(RR),或PPD≥4mm的齿数和BOP。在597名参与者的子样本中也评估了血清TNF-α和脂联素三分位数对IR-口腔炎症关联的潜在影响。

结果显示,基线时HOMA-IR最高三分位数的参与者,其BOP [RR = 1.19,95%置信区间(CI):1.03-1.36]和PPD≥4mm和BOP的牙数(RR = 1.39,95%置信区间:1.09 - 1.78),明显高于下两个HOMA-IR三分位组中的个体。TNF-α和脂联素都不会影响这些关联。

综上所述,该研究结果表明,IR可用于预测该人群中的牙龈/牙周炎症。

原始出处:

Andriankaja OM, Muñoz-Torres FJ, et al., Insulin resistance predicts the risk of gingival/periodontal inflammation. J Periodontol. 2018 Feb 20. doi: 10.1002/JPER.17-0384. [Epub ahead of print]

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    2018-03-30 baoya
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    2018-06-09 feather89
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    2018-03-11 天地飞扬

    了解一下.谢谢分享!

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