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Eur J Heart Fail:合并缺血性心脏病和终末期肾病的2型糖尿病患者心衰风险

2020-04-05 MedSci原创 MedSci原创

与未合并IHD和ESRD的患者相比,合并IHD、ESRD或两者都有的T2D患者发生HF的风险更高。预防IHD和ESRD可能是延缓或预防T2D患者HF发生的有效手段。

最近,心血管领域权威杂志European Journal of Heart Failure上发表了一篇研究文章,该研究旨在评估合并缺血性心脏病(IHD)、终末期肾病(ESRD)或两者都有的2型糖尿病(T2D)患者心衰(HF)的风险,并与无IHD和ESRD的T2D患者进行比较。

研究人员从丹麦全国的登记中心确定了1998年至2015年间所有新发T2D且无HF病史的患者。Landmark分析用于评估在几个随访时间内HF的5年绝对风险,并解释HF确诊之前IHD和ESRD的发生。

该研究共纳入了285024名新发T2D患者。在随访期间,19960名患者发生HF。在T2D诊断5年后未发生HF的患者中,无IHD和ESRD的患者发生HF的5年风险最低(4.02%;95%置信区间(CI)为3.90-4.15),合并IHD(11.51%;相对风险(RR)为2.86;95%CI为2.72-3.02;P<0.001)或ESRD(8.11%;RR为2.02;95%可信区间为1.39-2.93;P<0.001)的T2D患者具有中度风险,合并有IHD和ESRD患者(19.76%;RR为4.92;95%CI为3.43-7.05;P<0.001)的最高风险。

由此可见,与未合并IHD和ESRD的患者相比,合并IHD、ESRD或两者都有的T2D患者发生HF的风险更高。预防IHD和ESRD可能是延缓或预防T2D患者HF发生的有效手段。

原始出处:

Mariam E. Malik.et al.Risk of heart failure in type 2 diabetes complicated by incident ischaemic heart disease and end‐stage renal disease.European journal of heart failure.2020.https://doi.org/10.1002/ejhf.1819

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createdBy=80d715270048, createdName=slcumt, createdTime=Tue Apr 07 08:25:58 CST 2020, time=2020-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043046, encodeId=eba710430460b, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Apr 05 20:25:58 CST 2020, time=2020-04-05, status=1, ipAttribution=)]
    2020-04-07 zhaojie88
  5. 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  6. 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  7. 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  8. 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  9. 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    2020-04-07 slcumt
  10. 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    2020-04-05 misszhang

    谢谢MedSci提供最新的资讯

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