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Stroke:短期房性心律失常患者的卒中风险如何?

2017-11-17 xing.T MedSci原创

由此可见,短期AT增加卒中风险。因此,CHA2DS2-VASc评分可用于危险分层。房性早搏的负担和年龄是CHA2DS2-VASc评分为0或1的患者发生卒中的独立预测因子。

短期房性心律失常(AT)的患者发生卒中的风险仍不清楚。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,该研究旨在旨在探讨短期AT和卒中之间的关系,以及使用CHA2DS2-VASc评分进行危险分层的作用。

研究人员从24小时动态心电图监测登记中心招募了5342名无房颤或卒中的患者。短期AT被定义为阵发性室上性早搏短于5秒。

在1595例(29.8%)短期AT受试者中。在9年的中位随访期间,494名受试者发生了新发卒中。短期AT患者的卒中率明显高于无短期AT患者(11.4% vs. 8.3%,P<0.001)。短期AT患者中,对于CHA2DS2-VASc评分为0和1的受试者每100人每年的卒中人数分别为0.23和0.67。然而,CHA2DS2-VASC分值为2、3、4和≥5的受试者发生卒中的人数分别为1.62、1.89、1.30和2.91。CHA2DS2-VASc评分为0或1的受试者、年龄(大于61岁)和房性早搏负担(>25次/天)可以独立地预测卒中风险。在亚组分析中,短期AT患者基于他们的CHA2DS2-VASc评分被分为3组:低评分组(评分为0(男性)或1(女性),n=324),中等评分(评分为1(男性)或2(女性),n=275)和高评分组(评分为≥2(男性)或≥3(女性),n=996)。相比于低评分受试者,中等、高评分为卒中的独立预测因子(风险比为6.165,P<0.001,风险比为8.577,P<0.001)。

由此可见,短期AT增加卒中风险。因此,CHA2DS2-VASc评分可用于危险分层。房性早搏的负担和年龄是CHA2DS2-VASc评分为0或1的患者发生卒中的独立预测因子。

原始出处:

Shinya Yamada, et al. Risk of Stroke in Patients With Short-Run Atrial Tachyarrhythmia.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.018475

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    2017-11-18 lofter

    学习了感谢分享

    0

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    2017-11-17 Y—xianghai

    学习了新知识

    0

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    2017-11-17 杨利洪

    学习了提高了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1774871, encodeId=56e91e748715b, content=<a href='/topic/show?id=d6ce54226ce' target=_blank style='color:#2F92EE;'>#房性心律失常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54226, encryptionId=d6ce54226ce, topicName=房性心律失常)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc6238698305, createdName=luoxiaog, createdTime=Sun Dec 31 03:45:00 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281263, encodeId=11291281263c9, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sat Nov 18 21:45:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=262176, encodeId=f7252621e63d, content=学习了感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C20CB8E4EBB36F5B821651C710BCB491/100, createdBy=18de1715848, createdName=lofter, createdTime=Sat Nov 18 07:23:26 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261953, encodeId=f056261953a1, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Nov 17 08:06:39 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261934, encodeId=2e002619348c, content=学习了提高了, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Fri Nov 17 07:28:42 CST 2017, time=2017-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261917, encodeId=8ee126191e9f, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Nov 17 07:06:51 CST 2017, time=2017-11-17, status=1, ipAttribution=)]
    2017-11-17 明月清辉

    谢谢分享.学习了

    0

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