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Stroke:儿童身高和生长与首次缺血性卒中或脑出血有关!

2018-02-16 xing.T MedSci原创

由此可见,了解错过卒中预防机会的预测性病人特征,可能有助于初级保健识别和妥善管理这些个体。改善这些群体的管理可以减少他们的风险,并且可以预防未来大量的卒中和TIA患者。

卒中和短暂性脑缺血发作(TIA)的一级预防对于减轻这些疾病的负担非常重要;然而,预防性药物的处方欠佳。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员的目的是确定卒中/TIA前错过用降脂、抗凝或抗高血压药物进行预防性治疗机会相关的临床和人口学特征。

研究人员分析了来自于英国初级保健数据库中涵盖561个家庭的匿名电子医疗记录,纳入了在2009年1月1日和2013年12月31日期间诊断的首次卒中/短暂性脑缺血发作的年龄超过18岁的患者。错过预防机会被定义为临床上有降脂、抗凝或降压药物治疗指征的患者在卒中/TIA发生前未接受这些药物治疗。混合效应logistic回归模型用于评价错过预防机会与个体临床/人口学特征之间的关系。

符合纳入标准的有29043例卒中/TIA患者。冠心病、慢性肾脏病、外周动脉疾病或糖尿病患者错过降脂和降压药物处方的机会较少。然而,十年心血管疾病风险≥20%但没有这些诊断的患者错过降脂药物或抗高血压药物处方的风险增加。妇女不太可能开出抗凝剂的处方,但更可能开出降压药的处方。老年人(≥85岁)不太可能开出所有3种预防药物的处方,相比于年龄在75-79岁的个体。

由此可见,了解错过卒中预防机会的预测性病人特征,可能有助于初级保健识别和妥善管理这些个体。改善这些群体的管理可以减少他们的风险,并且可以预防未来大量的卒中和TIA患者。

原始出处:


Grace M. Turner,et al. Clinical and Demographic Characteristics Associated With Suboptimal Primary Stroke and Transient Ischemic Attack Prevention Retrospective Analysis.Stroke. 2018. https://doi.org/10.1161/STROKEAHA.117.020080

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1893020, encodeId=a5b31893020f4, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Oct 04 17:13:00 CST 2018, time=2018-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288999, encodeId=106428899999, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Feb 18 22:29:56 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806228, encodeId=6abf1806228d0, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sat Aug 11 07:13:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288614, encodeId=e355288614b8, content=学习了不少事情, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Sat Feb 17 08:51:52 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288591, encodeId=29192885911b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Feb 17 08:07:08 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-18 清风拂面

    谢谢分享学习

    0

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    2018-02-17 圣艮山

    学习了不少事情

    0

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    2018-02-17 yfjms

    学习

    0

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