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Diabetes Care:妊娠糖尿病诊断减少过度医疗

2012-07-19 范伟伟 医学论坛网

  《糖尿病护理》(Diabetes Care)杂志2012年7月11日在线发表的一项较大样本研究表明,采用国际糖尿病学会妊娠研究小组(IADPSG)的推荐将大幅度提高妊娠糖尿病(GDM)的诊断率。对IADPSG阳性妇女实施危险分层,可能有助于减少过度治疗。此外,空腹血糖(FPG)或体质指数(BMI)的筛查可能作为IADPSG建议的可行替代途径。   该研究旨在评价采用IADPSG的推

  《糖尿病护理》(Diabetes Care)杂志2012年7月11日在线发表的一项较大样本研究表明,采用国际糖尿病学会妊娠研究小组(IADPSG)的推荐将大幅度提高妊娠糖尿病(GDM)的诊断率。对IADPSG阳性妇女实施危险分层,可能有助于减少过度治疗。此外,空腹血糖(FPG)或体质指数(BMI)的筛查可能作为IADPSG建议的可行替代途径。

  该研究旨在评价采用IADPSG的推荐建议,对以色列妊娠糖尿病(GDM)筛查和诊断的重要性。此外,研究试图探索可行的方法,以确定女性不良妊娠结局的风险。

  研究分析了来自以色列血糖和不良妊娠结局研究的受试者数据(n=3345)。GDM阳性采用以下3种方法定义:①IADPSG标准;②IADPSG标准联合危险分层;或③采用BMI与空腹血糖(FPG)筛查;进一步计算受试者的不良结局事件发生率。

  结果表明,采纳IADPSG的建议后,将增加约50%的GDM诊断。IADPSG标准阳性的妇女有1/3为不良转归低风险患者,可以减少管理的强度。在妊娠28-32周采用FPG≥89 mg / dl或BMI≥33.5 kg/m2的标准,GDM的检出比例与IADPSG标准类似。

  链接:Ofra Kalter-Leibovici, MD1,2, Laurence S. Freedman, PHD3, Liraz Olmer, MA3, Nicky Liebermann, MD4, Anthony Heymann, MD5, Orna Tal, MD6, Liat Lerner-Geva, PHD2,7, Nir Melamed, MD2,8 and Moshe Hod, MD2,8 Screening and Diagnosis of Gestational Diabetes Mellitus. Critical appraisal of the new International Association of Diabetes in Pregnancy Study Group recommendations on a national level.Diabetes Care


    

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