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NEJM:双侧或单侧胸内动脉移植对GABG患者长期预后的影响

2019-02-01 zhangfan MedSci原创

研究认为,择期冠状动脉旁路移植患者接受双侧或单侧胸内动脉移植对长期预后的影响差异不大

冠状动脉旁路移植术(CABG)手术患者,接受多支动脉移植者其生存期优于单动脉移植者。近日研究人员考察了双侧胸内动脉移植对GABG患者生存期的影响。

择期接受GABG的患者随机接受双侧或单动脉移植者。研究的主要终点是10年后全因死亡,次要终点为全因死亡、心肌梗死或中风死亡。

1548名患者接受双侧移植,1554人接受单侧移植。在双侧移植组中,13.9%的患者仅接受胸内动脉移植,而在单侧移植组中,21.8%的患者还接受了桡动脉移植。10年中,双侧组315人死亡,单侧组329人(20.3% vs 21.2%,HR=0.96)。双侧组全因死亡、心肌梗死、脑卒中综合终点385例(24.9%),单侧组425例(27.3%,HR=0.90)。

研究认为,择期冠状动脉旁路移植患者接受双侧或单侧胸内动脉移植对长期预后的影响差异不大。

原始出处:

David P. Taggart, et al. Bilateral versus Single Internal-Thoracic-Artery Grafts at 10 Years.N Engl J Med, January 31, 2019.

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