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Rhinology:鼻腔分泌物中的特异性免疫球蛋白E可用于局部过敏性鼻炎的诊断

2019-06-12 AlexYang MedSci原创

最近,有研究人员在局部过敏性鼻炎(LAR)中详细调查了血清特异性免疫球蛋白E(slgE)和鼻过敏原激活测试(NAPT)的诊断价值。研究是一个前瞻性的单中心研究,总共包括了212名慢性鼻炎患者。其中73名患者为血清lgE阴性和局部嗜酸性粒细胞阳性。10名健康参与者为对照。所有的参与者完成了相关的调查问卷,并利用视觉模拟评分、血清slgE测试和NAPT对相关情况进行了评估。研究发现,14名患者具有阳性

最近,有研究人员在局部过敏性鼻炎(LAR)中详细调查了血清特异性免疫球蛋白E(slgE)和鼻过敏原激活测试(NAPT)的诊断价值。

研究是一个前瞻性的单中心研究,总共包括了212名慢性鼻炎患者。其中73名患者为血清lgE阴性和局部嗜酸性粒细胞阳性。10名健康参与者为对照。所有的参与者完成了相关的调查问卷,并利用视觉模拟评分、血清slgE测试和NAPT对相关情况进行了评估。研究发现,14名患者具有阳性的局部slgE结果。与对照相比,12名患者具有显著更高的局部slgE水平,且NAPT结果为阳性。VAS评分、鼻气道阻力和局部slgE、ECP、组胺和白三烯C4水平在NAPT后均显著增加。另外,slgE对LAR诊断的敏感度、特异性和诊断准确度分别为91.7%。

最后,研究人员指出,鼻腔分泌物中局部slgE水平的测量时LAR的一种可靠的和有效的诊断方法。

原始出处:


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    2019-08-03 gwc392
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    2019-07-06 xzw113
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    2019-06-14 chg122
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    2019-06-14 mnda

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记者7日从国家药监局获悉,上海方面对上海新兴医药股份有限公司生产的涉事批次静注人免疫球蛋白进行的艾滋病、乙肝、丙肝三种病毒核酸检测,结果均为阴性;江西方面对患者的艾滋病病毒核酸检测,结果为阴性。  国家药监局5日接到国家卫生健康委通报,上海新兴医药股份有限公司生产的一批次静注人免疫球蛋白(批号:20180610Z)艾滋病病毒抗体检测为阳性。国家药监局立即要求上海市药监局对上海新兴开展现场检查,组织

免疫球蛋白有艾滋?药监局公布调查结果…

日前,江西省疾控中心检测到上海某医药股份有限公司静注人免疫球蛋白(批号:20180610z)出现艾滋病抗体阳性事件引发大家广泛关注。随后,国家卫健委作出回应,要求立即开展药品排摸和封存工作,尽快查清事实,切实加强药品管理,确保群众用药安全。事情进展如何了?2月5日,国家卫健委接到上海某医药控股有限公司静注人免疫球蛋白艾滋病抗体阳性有关情况的报告后,立即通报国家药监局,并要求全国各医疗机构暂停使用和

Arthritis Rheumatol:预测利妥昔单抗治疗风湿和肌肉骨骼疾病期间严重感染和低丙种球蛋白血症的影响

应在基线和每个RTX周期之前监测免疫球蛋白,以识别有SIEs风险的患者。

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