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Medicine:丙泊酚全凭静脉麻醉并不会增加眼部手术术后眼内炎的发生率

2017-05-07 MedSci MedSci原创

既往研究表明,患者在全麻(GA)下接受眼部手术后患者的鼻咽分泌物会留在脸上,特别是在丙泊酚全静脉麻醉(TIVA),这可能会导致术后眼内炎。因此,本文进行了一项回顾性研究以对比眼部手术采用局麻、吸入麻醉以及TIVA术后眼内炎的发生率。 研究纳入了2011年至2015年就诊于本医疗中心的21032名患者。研究人员评估了流行病学因素、系统性疾病,以及其他眼部病理特征,术中并发症,眼外科技术,预防性

既往研究表明,患者在全麻(GA)下接受眼部手术后患者的鼻咽分泌物会留在脸上,特别是在丙泊酚全静脉麻醉(TIVA),这可能会导致术后眼内炎。因此,本文进行了一项回顾性研究以对比眼部手术采用局麻、吸入麻醉以及TIVA术后眼内炎的发生率。

研究纳入了2011年至2015年就诊于本医疗中心的21032名患者。研究人员评估了流行病学因素、系统性疾病,以及其他眼部病理特征,术中并发症,眼外科技术,预防抗生素的应用,玻璃体,以及视力情况。

结果共有15名患者术后发生眼内炎,相当于发生率为0.071%。局麻、吸入性麻醉,以及基于TIVA的麻醉术后眼内炎的发生率分别为0.083%、0.039%和0%(P = 0.39  )。此外,GA下眼内炎的发生风险(0.024%)显著低于局部麻醉(0.083%)(P<0.001  )。研究人员还发现,老年是眼内手术术后眼内炎发生的一个危险因素。

总而言之,研究结果表明,丙泊酚全凭静脉麻醉和吸入麻醉并没有增加眼部手术术后眼内炎的发生风险。因此,GA并不是术后眼内炎的危险因素。相比之下,老龄则是术后眼内炎发生的一个危险因素。

原始出处:


Lai HC, Tseng WC, et al., Relationship between anesthesia and postoperative endophthalmitis: A retrospective study. Medicine (Baltimore). 2017 Mar;96(12):e6455. doi: 10.1097/MD.0000000000006455.

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    2017-07-22 fusion
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encryptionId=508ae2913d6, topicName=眼部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=126338864246, createdName=huiwelcome, createdTime=Fri Sep 15 16:51:00 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773616, encodeId=a29b1e73616de, content=<a href='/topic/show?id=5f014e1852' target=_blank style='color:#2F92EE;'>#CIN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4718, encryptionId=5f014e1852, topicName=CIN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9a038523631, createdName=kalseyzl, createdTime=Sat Aug 26 08:51:00 CST 2017, time=2017-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1858742, encodeId=823a1858e42dd, content=<a href='/topic/show?id=e0a9593596' target=_blank style='color:#2F92EE;'>#DIC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Thu Mar 29 10:51:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224687, encodeId=8fa422468e87, content=队列研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51181430378, createdName=ff4027, createdTime=Fri Jul 21 15:51:08 CST 2017, time=2017-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038295, encodeId=0aba203829501, content=<a href='/topic/show?id=4d0999208f8' target=_blank style='color:#2F92EE;'>#静脉麻醉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99208, encryptionId=4d0999208f8, topicName=静脉麻醉)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Aug 07 07:51:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577525, encodeId=28da15e75250a, content=<a href='/topic/show?id=cda91148004' target=_blank style='color:#2F92EE;'>#Medicine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11480, encryptionId=cda91148004, topicName=Medicine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=54cd16396700, createdName=ms1692212821629096, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607483, encodeId=b9f3160e4830a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
    2017-09-15 huiwelcome
  5. [GetPortalCommentsPageByObjectIdResponse(id=1693381, encodeId=75831693381e9, content=<a href='/topic/show?id=84a9e272175' target=_blank style='color:#2F92EE;'>#眼内炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72721, encryptionId=84a9e272175, topicName=眼内炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63ee29418707, createdName=liuyong2990, createdTime=Wed Sep 13 05:51:00 CST 2017, time=2017-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1697455, encodeId=ba11169e455b3, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, 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channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Thu Mar 29 10:51:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224687, encodeId=8fa422468e87, content=队列研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51181430378, createdName=ff4027, createdTime=Fri Jul 21 15:51:08 CST 2017, time=2017-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038295, encodeId=0aba203829501, content=<a href='/topic/show?id=4d0999208f8' target=_blank style='color:#2F92EE;'>#静脉麻醉#</a>, beContent=null, objectType=article, channel=null, level=null, 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GetPortalCommentsPageByObjectIdResponse(id=1607483, encodeId=b9f3160e4830a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
    2017-08-26 kalseyzl
  6. [GetPortalCommentsPageByObjectIdResponse(id=1693381, encodeId=75831693381e9, content=<a href='/topic/show?id=84a9e272175' target=_blank style='color:#2F92EE;'>#眼内炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72721, encryptionId=84a9e272175, topicName=眼内炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63ee29418707, createdName=liuyong2990, createdTime=Wed Sep 13 05:51:00 CST 2017, time=2017-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1697455, encodeId=ba11169e455b3, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, 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channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5935, encryptionId=e0a9593596, topicName=DIC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7770, createdName=jeanqiuqiu, createdTime=Thu Mar 29 10:51:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=224687, encodeId=8fa422468e87, content=队列研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51181430378, createdName=ff4027, createdTime=Fri Jul 21 15:51:08 CST 2017, time=2017-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038295, encodeId=0aba203829501, content=<a href='/topic/show?id=4d0999208f8' target=_blank style='color:#2F92EE;'>#静脉麻醉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99208, encryptionId=4d0999208f8, topicName=静脉麻醉)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Mon Aug 07 07:51:00 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577525, encodeId=28da15e75250a, content=<a href='/topic/show?id=cda91148004' target=_blank style='color:#2F92EE;'>#Medicine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11480, encryptionId=cda91148004, topicName=Medicine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=54cd16396700, createdName=ms1692212821629096, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607483, encodeId=b9f3160e4830a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
    2018-03-29 jeanqiuqiu
  7. [GetPortalCommentsPageByObjectIdResponse(id=1693381, encodeId=75831693381e9, content=<a href='/topic/show?id=84a9e272175' target=_blank style='color:#2F92EE;'>#眼内炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72721, encryptionId=84a9e272175, topicName=眼内炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63ee29418707, createdName=liuyong2990, createdTime=Wed Sep 13 05:51:00 CST 2017, time=2017-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1697455, encodeId=ba11169e455b3, content=<a href='/topic/show?id=f2399910109' target=_blank style='color:#2F92EE;'>#静脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99101, encryptionId=f2399910109, topicName=静脉)], attachment=null, authenticateStatus=null, createdAvatar=null, 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GetPortalCommentsPageByObjectIdResponse(id=1607483, encodeId=b9f3160e4830a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue May 09 10:51:00 CST 2017, time=2017-05-09, status=1, ipAttribution=)]
    2017-07-21 ff4027

    队列研究

    0

  8. 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  9. 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  10. 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