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2019ESMO-Asia:Darolutamide延缓非转移性前列腺癌患者的疾病进展和化疗时间

2019-11-28 Allan MedSci原创

根据在2019年欧洲医学肿瘤学会(ESMO)亚洲大会上发表的一项研究,Darolutamide延缓了非转移性去势抵抗性前列腺癌患者的疾病进展和开始化疗的时间。

根据在2019年欧洲医学肿瘤学会(ESMO)亚洲大会上发表的一项研究,Darolutamide延缓了非转移性去势抵抗性前列腺癌患者的疾病进展和开始化疗的时间。

ARAMIS试验中的患者被随机分配接受每日两次600毫克的darolutamiden = 955)或安慰剂(n = 554)。两组患者继续接受雄激素剥夺治疗。医学博士Jung See-Tong Pang表示:与安慰剂相比,Darolutamide延缓了去势抵抗性前列腺癌患者的疾病进展和开始化疗治疗,同时保持了生活质量,并且没有增加关键不良事件的发生率。与安慰剂相比,Darolutamide将进展时间显著延迟了26个月(33个月 vs. 7个月)。


原始出处:

https://www.firstwordpharma.com/node/1683960?tsid=4

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    2020-09-08 liuhuangbo
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createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423378, encodeId=3da314233e81f, content=<a href='/topic/show?id=48e55e0461' target=_blank style='color:#2F92EE;'>#darolutamide#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5704, encryptionId=48e55e0461, topicName=darolutamide)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab13776446, createdName=yangcx0916, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1907722, encodeId=4e22190e72202, content=<a href='/topic/show?id=fdcee0731d2' target=_blank style='color:#2F92EE;'>#疾病进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70731, encryptionId=fdcee0731d2, topicName=疾病进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Tue Jun 02 05:20:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2024883, encodeId=509a2024883b4, content=<a href='/topic/show?id=c27516459de' target=_blank style='color:#2F92EE;'>#SMO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16459, encryptionId=c27516459de, topicName=SMO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Tue Sep 08 06:20:00 CST 2020, time=2020-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976581, encodeId=858719e65817c, content=<a href='/topic/show?id=29a09340656' target=_blank style='color:#2F92EE;'>#转移性前列腺癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93406, encryptionId=29a09340656, topicName=转移性前列腺癌患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Wed Dec 04 20:20:00 CST 2019, time=2019-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1819681, encodeId=27611819681df, content=<a href='/topic/show?id=b018996931d' target=_blank style='color:#2F92EE;'>#非转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99693, encryptionId=b018996931d, topicName=非转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Jul 22 05:20:00 CST 2020, time=2020-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080157, encodeId=d8c6208015e86, content=<a href='/topic/show?id=fc8c9969495' target=_blank style='color:#2F92EE;'>#非转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99694, encryptionId=fc8c9969495, topicName=非转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Sep 11 00:20:00 CST 2020, time=2020-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780106, encodeId=3f521e8010602, content=<a href='/topic/show?id=10d62860dd' target=_blank style='color:#2F92EE;'>#ASIA#</a>, beContent=null, objectType=article, 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href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1395545, encodeId=2bc913955458f, content=<a href='/topic/show?id=7bbf93405a5' target=_blank style='color:#2F92EE;'>#转移性前列腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93405, encryptionId=7bbf93405a5, topicName=转移性前列腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/656F31B644588474D1C46903A7F84373/100, createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423378, encodeId=3da314233e81f, content=<a href='/topic/show?id=48e55e0461' target=_blank style='color:#2F92EE;'>#darolutamide#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5704, encryptionId=48e55e0461, topicName=darolutamide)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab13776446, createdName=yangcx0916, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1907722, encodeId=4e22190e72202, content=<a href='/topic/show?id=fdcee0731d2' target=_blank style='color:#2F92EE;'>#疾病进展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70731, encryptionId=fdcee0731d2, topicName=疾病进展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Tue Jun 02 05:20:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2024883, encodeId=509a2024883b4, content=<a href='/topic/show?id=c27516459de' target=_blank style='color:#2F92EE;'>#SMO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16459, encryptionId=c27516459de, topicName=SMO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, 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href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1395545, encodeId=2bc913955458f, content=<a href='/topic/show?id=7bbf93405a5' target=_blank style='color:#2F92EE;'>#转移性前列腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93405, encryptionId=7bbf93405a5, topicName=转移性前列腺癌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/656F31B644588474D1C46903A7F84373/100, createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423378, encodeId=3da314233e81f, content=<a href='/topic/show?id=48e55e0461' target=_blank style='color:#2F92EE;'>#darolutamide#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5704, encryptionId=48e55e0461, topicName=darolutamide)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab13776446, createdName=yangcx0916, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=)]
    2020-04-13 luwei00
  7. 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createdBy=4e842500199, createdName=ms24272190615788285182, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423378, encodeId=3da314233e81f, content=<a href='/topic/show?id=48e55e0461' target=_blank style='color:#2F92EE;'>#darolutamide#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5704, encryptionId=48e55e0461, topicName=darolutamide)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab13776446, createdName=yangcx0916, createdTime=Sat Nov 30 00:20:00 CST 2019, time=2019-11-30, status=1, ipAttribution=)]
    2019-11-30 zhang92560
  8. 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  9. 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  10. 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