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JACC:二尖瓣修复术后的远期预后研究

2019-09-08 不详 MedSci原创

二尖瓣修复术已经成为退行性二尖瓣反流(MR)患者的标准治疗方法,但其远期预后尚不清楚。本研究的目的旨在评估二尖瓣修复术对MR的远期影响。本研究纳入分析了1234名(平均年龄59岁,男性占70.4%)接受二尖瓣修复术的MR患者,平均随访时间为13年(8-34年)。在第20年,不用再手术的患者生存率为60.4%(95%Cl:56.2%-64.2%),心脏和瓣膜相关的累积死亡率为12%,非心脏相关死亡率

二尖瓣修复术已经成为退行性二尖瓣反流(MR)患者的标准治疗方法,但其远期预后尚不清楚。本研究的目的旨在评估二尖瓣修复术对MR的远期影响。

本研究纳入分析了1234名(平均年龄59岁,男性占70.4%)接受二尖瓣修复术的MR患者,平均随访时间为13年(8-34年)。在第20年,不用再手术的患者生存率为60.4%(95%Cl:56.2%-64.2%),心脏和瓣膜相关的累积死亡率为12%,非心脏相关死亡率为21.3%,感染性心内膜炎发生率为1.1%,血栓栓塞发生率为10.3%,出血发生率为6.4%。中重度MR的复发率为12.5%,持续性或新发的三尖瓣反流(TR)发生率为20.8%,新发房颤率为32.4%。多变量分析显示高龄、完全性房室传导阻滞、二尖瓣粘液瘤的程度与MR的复发呈相关性。房颤和TR的发生与MR的复发无明显相关性。

研究结果显示,二尖瓣修复术后的二尖瓣反流复发、三尖瓣反流和房颤随着时间推移发生率逐渐增高。

原始出处:

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    2020-02-17 hbwxf
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    2020-04-16 1371f3708cm

    学习

    0

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    2019-09-10 wwzzly

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