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Heart:心肌病和心力衰竭的流行病学数据

2022-01-09 MedSci原创 MedSci原创

所有记录的心肌病患病率在过去十年中都有所增加。CA的诊断通常早于心力衰竭,而ARVC或肥厚性心肌病的个体在其心肌病诊断后更容易发展为心力衰竭。

心肌病是由心室心肌的结构和功能异常定义的疾病,不能仅由冠状动脉疾病(CAD)或异常负荷状况解释。 心肌病患者可能出现心力衰竭、心律失常、晕厥、胸痛和心源性猝死(SCD)。心肌病的人群患病率以及症状性心力衰竭和心肌病表型心律失常的自然病程尚未完全明确。

近日,心脏病领域权威杂志Heart上发表了一篇研究文章,该研究旨在评估人群诊断的心肌病患病率,并阐明心力衰竭与心律失常与心肌病诊断之间的时间关系。

研究人员从关联的电子健康记录(约9百万人;2000-2018年)中识别出心肌病患者(n=4116),并将其分为肥厚型心肌病、扩张型心肌病(DCM)、致心律失常性右心室心肌病(ARVC)、限制性心肌病(RCM)和心脏淀粉样变性(CA)。研究人员确定了心肌病的点患病率、症状性心力衰竭和心律失常的发生率以及与心肌病诊断相关的时间。

在2018年,DCM是最常见的心肌病。DCM和肥厚性心肌病在男性中的发病率是女性的两倍,而ARVC的趋势相反。在2010年至2018年期间,ARVC的患病率增加了180%,肥厚性心肌病的患病率增加了9%。在诊断时,与ARVC(29%)和肥厚性心肌病(27%)相比,更多的CA(66%)、DCM(56%)和RCM(62%)患者既往会出现心力衰竭。在心肌病诊断时没有心力衰竭的患者中,CA和DCM的年化心力衰竭发生率最高。所有心肌病的诊断都集中在心力衰竭发作时间。

由此可见,所有记录的心肌病患病率在过去十年中都有所增加。CA的诊断通常早于心力衰竭,而ARVC或肥厚性心肌病的个体在其心肌病诊断后更容易发展为心力衰竭。

原始出处:

Jack RW Brownrigg.et al.Epidemiology of cardiomyopathies and incident heart failure in a population-based cohort study.heart.2022.https://heart.bmj.com/content/early/2021/12/28/heartjnl-2021-320181

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    2022-01-17 1485ff0bm61暂无昵称

    学习了

    0

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    2022-01-12 染尘

    0

  4. 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createdName=ms5000000254917531, createdTime=Sun Jan 09 16:24:26 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357860, encodeId=c221135e860c0, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411409, encodeId=ddd61411409b0, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563572, encodeId=9c6515635e28f, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622519, encodeId=a5b0162251991, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-12 ms6000000225486324

    很好

    0

  5. 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createdName=ms5000000254917531, createdTime=Sun Jan 09 16:24:26 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357860, encodeId=c221135e860c0, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411409, encodeId=ddd61411409b0, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563572, encodeId=9c6515635e28f, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622519, encodeId=a5b0162251991, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-09 183068291

    学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1201358, encodeId=a0451201358ed, content=<a href='/topic/show?id=c65251303fc' target=_blank style='color:#2F92EE;'>#心肌病#</a>与<a href='/topic/show?id=072c5088466' target=_blank style='color:#2F92EE;'>#心力衰竭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51303, encryptionId=c65251303fc, topicName=心肌病), TopicDto(id=50884, encryptionId=072c5088466, topicName=心力衰竭)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=医者仁者, createdTime=Thu Mar 10 14:51:59 CST 2022, time=2022-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1185110, encodeId=483811851109a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3b05290128, createdName=1485ff0bm61暂无昵称, createdTime=Mon Jan 17 09:32:31 CST 2022, time=2022-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183708, encodeId=d7ed1183e08da, content=还, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ef5561744, createdName=染尘, createdTime=Wed Jan 12 23:50:24 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183548, encodeId=c6bd118354857, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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createdName=ms5000000254917531, createdTime=Sun Jan 09 16:24:26 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357860, encodeId=c221135e860c0, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411409, encodeId=ddd61411409b0, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563572, encodeId=9c6515635e28f, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622519, encodeId=a5b0162251991, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-09 ms5000000254917531

    很不错

    0

  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3b05290128, createdName=1485ff0bm61暂无昵称, createdTime=Mon Jan 17 09:32:31 CST 2022, time=2022-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183708, encodeId=d7ed1183e08da, content=还, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96ef5561744, createdName=染尘, createdTime=Wed Jan 12 23:50:24 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183548, encodeId=c6bd118354857, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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createdName=ms5000000254917531, createdTime=Sun Jan 09 16:24:26 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357860, encodeId=c221135e860c0, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1411409, encodeId=ddd61411409b0, content=<a href='/topic/show?id=91e96538eee' target=_blank style='color:#2F92EE;'>#流行病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65387, encryptionId=91e96538eee, topicName=流行病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563572, encodeId=9c6515635e28f, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622519, encodeId=a5b0162251991, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-09 zhaojie88
  8. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-09 xugumin
  9. 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level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Jan 09 09:47:39 CST 2022, time=2022-01-09, status=1, ipAttribution=)]
    2022-01-09 slcumt
  10. 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