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新的研究表明大麻和精神分裂症之间可相互影响

2016-12-31 MedSci MedSci原创

近日发表在Psychological Medicine的一项新的研究指出精神分裂和使用大麻之间存在联系。不仅是有精神分裂倾向的人更易尝试大麻,而且大麻可能增加症状发展的风险。研究表明使用大麻在精神病患者中比在普通人群中更常见,并可能增加精神病症状的风险。其使用和精神病症状有关联,如偏执狂和妄想,高达40%的使用者。然而,研究结果并不确定,专家呼吁进行更多研究。研究人员探究了可能预测一个人是否使用大

近日发表在Psychological Medicine的一项新的研究指出精神分裂和使用大麻之间存在联系。不仅是有精神分裂倾向的人更易尝试大麻,而且大麻可能增加症状发展的风险。


研究表明使用大麻在精神病患者中比在普通人群中更常见,并可能增加精神病症状的风险。其使用和精神病症状有关联,如偏执狂和妄想,高达40%的使用者。

然而,研究结果并不确定,专家呼吁进行更多研究。研究人员探究了可能预测一个人是否使用大麻的遗传因素,以及他们是否可能发展为精神分裂。数据取自大范围的基因组研究。使用孟德尔随机化技术分析数据,使作者能解释一系列变异体。选择该技术是因为研究团队预测使用大麻的人们可能在基因和生物上以各种方式和不使用的人不同。
                            
研究结果显示开始使用大麻可能增加精神分裂的风险,但特别的是有精神分裂风险的人更可能使用大麻。这可能是因为精神分裂的遗传因素比使用大麻的遗传因素更强。

由于结果显示精神分裂患者更可能是大麻的大量使用者,作者想研究是否基因联系可以解释使用大麻的程度。

团队中的一员,Marcus Munafò教授猜测“和精神分裂相关的某些行为和症状可能被大麻的作用缓解。”换句话说,使用大麻可能是这类人群的一种自我用药。另一种解释是“精神分裂症的高危人群可能更多地享受大麻的心理影响。

“大家越来越一致认为大麻的使用可能会增加发展精神分裂症的风险。我们的研究结果支持这一点,但也表明那些处于精神分裂症风险增加的人更可能首先尝试大麻。

原始出处:


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    2017-01-18 明心见性

    精神健康,远离大麻

    0

  2. 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    2017-01-14 三生有幸9135

    学习一下,谢谢你的分享

    0

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    2017-01-04 大爰

    再次学习并分享感谢

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Tue Jan 03 16:18:52 CST 2017, time=2017-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=167595, encodeId=5ad816e5956b, content=使用大麻易患精神病,精神病人喜欢用大麻。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Jan 03 05:56:39 CST 2017, time=2017-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=167533, encodeId=edbf16e5334c, content=对精神分裂症研究有帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Mon Jan 02 08:18:41 CST 2017, time=2017-01-02, status=1, ipAttribution=)]
    2017-01-03 邓启付

    大麻的临床运用还是要谨慎。

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Mon Jan 02 08:18:41 CST 2017, time=2017-01-02, status=1, ipAttribution=)]
    2017-01-03 1e0f8808m18(暂无匿称)

    使用大麻易患精神病,精神病人喜欢用大麻。

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Mon Jan 02 08:18:41 CST 2017, time=2017-01-02, status=1, ipAttribution=)]
    2017-01-02 xiehhtt

    对精神分裂症研究有帮助

    0

  7. 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  8. 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    2017-01-02 kcb069
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    2017-01-02 1e0f8808m18(暂无匿称)

    远离毒品,保卫精神。

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Mon Jan 02 08:18:41 CST 2017, time=2017-01-02, status=1, ipAttribution=)]
    2017-01-02 邓启付

    大麻的使用对增加精神分裂症的风险很大。

    0

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