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JACC:体重增加期间进食脂肪类型影响脂质谱

2014-10-24 高晓方 译 医学论坛网

瑞典一项研究表明,体重增加期间进食多不饱和脂肪酸(PUFA)的个体致动脉粥样硬化脂蛋白降低,进食多饱和脂肪酸(SFA)者则升高。论文于10月15日在线发表于《美国心脏病学会杂志》。 此项为期7周的研究共纳入39例健康消瘦受试者,并通过进食约三个松饼的方式使受试者每日额外摄入750 kcal。除脂肪类型不同之外,松饼的制备方法均相同。19例受试者的进食的松饼由来自于葵花籽油的PUFA制成,其余20

瑞典一项研究表明,体重增加期间进食多不饱和脂肪酸(PUFA)的个体致动脉粥样硬化脂蛋白降低,进食多饱和脂肪酸(SFA)者则升高。论文于10月15日在线发表于《美国心脏病学会杂志》。[pdf free]


此项为期7周的研究共纳入39例健康消瘦受试者,并通过进食约三个松饼的方式使受试者每日额外摄入750 kcal。除脂肪类型不同之外,松饼的制备方法均相同。19例受试者的进食的松饼由来自于葵花籽油的PUFA制成,其余20例受试者进食的松饼则富含来自于棕榈油的SFA。

结果显示,两组受试者的体重均增加2.2%(约1.5kg)。PUFA和SFA组在体重增加方面无显著差异,但在总胆固醇/HDL胆固醇、LDL/HDL胆固醇以及载脂蛋白B(apoB)/载脂蛋白A1(apoA1)方面两组存在显著差异。在摄食过度期间,PUFA组的上述比值分别比SFA组降低13%、19和16%。PUFA组的非HDL胆固醇呈降低趋势。两组受试者的空腹胰岛素、胰岛素原和胰岛素抵抗均升高。

原始出处:

Iggman D1, Rosqvist F2, Larsson A3, Arnlöv J4, Beckman L5, Rudling M5, Risérus U2.Role of Dietary Fats in Modulating Cardiometabolic Risk During Moderate Weight Gain: A Randomized Double-Blind Overfeeding Trial (LIPOGAIN Study).J Am Heart Assoc. 2014 Oct 15;3(5). pii: e001095. doi: 10.1161/JAHA.114.001095.[pdf free]

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    2015-06-30 hbwxf
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    2014-10-26 jeanqiuqiu
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    2014-10-26 gj0737
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