新药物有望提高哮喘疗效

2016-08-17 张家伟新华社

一个

一个国际团队日前在英国医学期刊《柳叶刀·呼吸医学》上发表报告说，一种新药物在治疗哮喘的临床试验中显示了非常不错的疗效，大大减轻了患者的症状，未来或许能为这方面的治疗带来新变化。

哮喘是一种常见的呼吸系统疾病，属于慢性气道炎症，其症状包括喘息、呼吸急促、胸闷以及咳嗽等。由英国莱斯特大学研究人员领衔的团队报告说，他们开发出一种名为Fevipiprant的新药，能够缓解哮喘症状，改善肺部功能，减轻炎症。

这种药物已进行了初步的临床试验，61名哮喘患者被分成两组，他们都仍然服用原来的药物。在此基础上，其中一组患者再服用新药，而另一组患者再服用安慰剂。研究人员检测了这些患者痰液中的嗜酸性粒细胞比例，通常哮喘症状中等至严重程度患者的这个比例约为5％。在12周后，服用新药一组患者的这个比例从平均5.4％下降到1.1％。

报告作者之一、莱斯特大学教授克里斯托弗·布莱特灵说，这种药物能够降低哮喘症状发作的次数，从而改善患者的生活质量，未来或许能给这方面的治疗带来革命性变化。

原始出处

Sherif Gonem, PhD*, Rachid Berair, MBChB*, Amisha Singapuri, BSc, Ruth Hartley, MBChB, Marie F M Laurencin, BSc, Gerald Bacher, PhD, Björn Holzhauer, Dipl Math, Michelle Bourne, BSc, Vijay Mistry, BSc, Prof Ian D Pavord, DM, Adel H Mansur, PhD, Prof Andrew J Wardlaw, PhD, Prof Salman H Siddiqui, PhD, Richard A Kay, PhD†, Prof Christopher E Brightling, PhD†,correspondencePress enter key for correspondence informationemail.Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial.Lancet Respiratory Medicine。2016

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2016-10-06 ms1065684921169360

#新药物#

73 0
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2016-08-24 曹～～

希望新药更好！别太贵就好

129 0
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2016-08-20 doctorJiangchao

继续学习

94 0
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2016-08-20 doctorJiangchao

继续关注

0 0
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2016-08-18 忠诚向上

好好学习一下

139 0
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2016-08-17 doctorJiangchao

继续学习

108 0
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2016-08-17 doctorJiangchao

继续关注

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