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Neurology:貌似钻孔的扩大顶骨孔

2019-10-30 zyx 神经科病例撷英拾粹

49岁女性,表现为偏头痛持续状态。尽管没有先前的颅骨手术,但头颅CT可见后旁正中颅盖双侧对称钻孔.

49岁女性,表现为偏头痛持续状态。尽管没有先前的颅骨手术,但头颅CT可见后旁正中颅盖双侧对称钻孔(图)。这些洞最终证实为扩大顶骨孔(enlarged parietal foramina,EPF),与其临床表现无关。EPF是顶骨的罕见发育缺陷(患病率为1:15000-50000),通常是因异质同源框基因突变出现异常骨化模式。EPF很少与颅面部和血管畸形,头痛以及癫痫有关,多为良性,属于偶然发现,直径从数毫米到数厘米不等,且通常位于上,后顶骨。


(图:CT和X片可见对称卵圆孔,直径约50×50mm,贯穿整个顶骨深度,符合EPF)

原始出处:Fernandez J, Woodson S, Cannard K. Teaching NeuroImages: Enlarged parietal foramina inadvertently labeled as burr holes. Neurology. 2019 Aug 20;93(8):e827-e828.

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