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CHEST:儿童阻塞性呼吸睡眠呼吸障碍知多少?

2016-12-27 MedSci MedSci原创

尽管最近的临床指南取得了一定发展,但是对儿童的阻塞性睡眠呼吸障碍(oSDB)症状的最佳护理途径仍有争议。近期,一项发表在CHEST杂志上的文章系统评价了迄今为止所进行的儿童oSDB数据库研究,以支持进一步的指南制定,确定证据差距和指导未来的研究。此项研究系统地搜索了自2015年11月26日始的PubMed、Embase和Cochrane Library数据库。包括所有关于儿童oSDB的出版物。计算

尽管最近的临床指南取得了一定发展,但是对儿童的阻塞性睡眠呼吸障碍(oSDB)症状的最佳护理途径仍有争议。

近期,一项发表在CHEST杂志上的文章系统评价了迄今为止所进行的儿童oSDB数据库研究,以支持进一步的指南制定,确定证据差距和指导未来的研究。

此项研究系统地搜索了自2015年11月26日始的PubMed、Embase和Cochrane Library数据库。包括所有关于儿童oSDB的出版物。计算oSDB年度出版物的数量;计算了自2011年1月1日以来发表文献(即美国儿科学会指南的最新文献检索日期)的主要研究主题和方法的出版物总数和年度数。

此项研究最终在检索的7637条记录中,有5871条出版物符合纳入标准。自2000年以来,年刊的出版量有所增加。大多数(61%)出版物着重于个体治疗方式、发病率或预后。很少(2.7%)出版物侧重于卫生服务提供、结局和健康经济。其中有78.5%的出版物是观察性的研究,2.4%是随机对照试验,0.4%使用定性方法作为主要研究方法。

最后,此项研究得出结论:近期关于儿童oSDB的研究激增,改善了这种状况的知识基础;但是缺乏卫生服务、卫生经济学和结果研究。这些影响着目前指导证据的适用性,并为今后的研究留下重要问题。

原始出处:
Venekamp RP, Chandrasekharan D, Abel F, Blackshaw H, Kreis IA, Evans H, Schilder AG. What has been researched in childhood obstructive sleep-disordered breathing: a systematic review. Chest. 2016 Dec 14. pii: S0012-3692(16)62586-2. doi: 10.1016/j.chest.2016.12.001.

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    2017-07-09 Smile2680
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    2017-05-28 tomyang96
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