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Brit J Cancer:中国成人肥胖与结肠直肠癌和小肠癌的风险!

2018-06-08 xing.T MedSci原创

由此可见,在相对精瘦的中国成年人中,肥胖与结肠癌和直肠癌的风险相关,男性比女性相关性更密切。

关于肥胖与中国肠癌及其解剖亚型之间的关联仍然存在不确定性。近日,肿瘤领域权威杂志British Journal of Cancer上针对这一问题发表了一篇研究文章。

在10年随访期间,对于509568名基线时无癌症的参与者,中国前瞻性的Kadoorie生物库中记录了3024例结肠直肠癌(CRC)患者和143例小肠癌(SIC)癌患者。研究人员采用Cox回归分析估计了与肥胖相关的特定癌症调整后的风险比(HRs)。

总体平均体重指数(BMI)为23.7kg/m2。BMI与CRC(每增加一个SD风险比为1.10(95%CI为1.06-1.14))、结肠(1.13(1.07-1.18))和直肠癌(1.07(1.02-1.13))呈正相关。对于腰围,每增加一个SD对应的风险比分别为1.14(1.10-1.18)、1.18(1.13-1.24)和1.11(1.05-1.16)。男性调整后的HRs比女性略高。肥胖与SIC风险呈正相关,但不显著。

由此可见,在相对精瘦的中国成年人中,肥胖与结肠癌和直肠癌的风险相关,男性比女性相关性更密切。

原始出处:

 
Yuanjie Pang,et al. Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people.British Journal of Cancer. 2018. https://www.nature.com/articles/s41416-018-0124-8
 
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    2019-05-08 lfyang
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    2018-06-18 溜溜梅不酸

    在相对精瘦的中国成年人中.肥胖与结肠癌和直肠癌的风险相关.男性比女性相关性更密切.

    0

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    2018-06-11 121832a9m88暂无昵称

    学习了

    0

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    2018-06-10 phoebeyan520

    学习了受益匪浅!

    0

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    2018-06-08 1e0f8808m18(暂无匿称)

    减肥降低消化道癌症风险.

    0

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    2018-06-08 龙胆草

    学习谢谢分享

    0

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