Baidu
map

Lasers Med Sci:激光能否有效治疗黄褐斑?

2022-07-29 sunshine MedSci原创

黄褐斑是一种高发的、有损外观的色素性皮肤病。治疗后的效果往往不尽人意。大量的临床试验试图证明涉及激光治疗的综合疗法的有效性,但结果并不确定。

黄褐斑是一种高发的、有损外观的色素性皮肤病。治疗后的效果往往不尽人意。大量的临床试验试图证明涉及激光治疗的综合疗法的有效性,但结果并不确定。近日,发表于Lasers Med Sci的一项系统回顾和荟萃分析评估了激光治疗黄褐斑的有效性。

研究人员分别检索了4个数据库和clinicaltrials.gov截至2021年6月8日收录的相关文献。两位研究人员独立搜索文献并提取数据。通过加权平均差异(WMD)计算研究结果。所有的统计分析都是由Review Manager 5.3版、STATA 14版软件在95%的置信区间内进行的。

结果,研究人员共纳入了22项符合条件的研究,包括694名患者。经过异质性检验和敏感性分析,对不同类型的激光治疗前后的情况进行了亚组荟萃分析。结果发现,大多数激光和基于激光的组合与黄褐斑面积和严重程度指数(MASI)的降低有关,如低流量Q-switch 1,064纳米Nd:YAG激光(QSNYL)(WMD:-2. 76;95%CI:-3.53至-1.99),点阵消融式二氧化碳激光(WMD:-9.36;95%CI:-12.51至-6.21),以及点阵消融式2940-纳米Er:YAG激光(WMD:-2,72;95%CI:-3.94至-1.49)。非剥脱性1550纳米点阵激光(WMD: -1.29; 95% CI: -2.80 to 0.21)和皮秒激光(WMD: -0.58; 95% CI: -1.43 to 0.27)的MASI评分和低流量QSNYL治疗的黑色素指数(MI)均未见明显下降。使用激光治疗黄褐斑时,可能会出现各种不良反应,其中大部分会在不进行后续治疗的情况下迅速解决,如治疗后出现水肿、红斑、脱屑、烧灼感等。然而,对于皮肤较黑的患者来说,存在着炎症后色素沉着和色素减退的风险。

综上所述,该项系统回顾和荟萃分析显示,激光和基于激光的联合治疗黄褐斑可以显著降低MASI评分。

原始出处:

Dihui Lai, et al., Laser therapy in the treatment of melasma: a systematic review and meta-analysis. Lasers Med Sci. 2022 Jun;37(4):2099-2110. doi: 10.1007/s10103-022-03514-2.  

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1878566, encodeId=7a0818e856601, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Fri Dec 16 00:45:58 CST 2022, time=2022-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279824, encodeId=fe3312e98242b, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611675, encodeId=e4ae16116e580, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619651, encodeId=48331619651e3, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=)]
    2022-12-16 anminleiryan
  2. [GetPortalCommentsPageByObjectIdResponse(id=1878566, encodeId=7a0818e856601, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Fri Dec 16 00:45:58 CST 2022, time=2022-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279824, encodeId=fe3312e98242b, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611675, encodeId=e4ae16116e580, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619651, encodeId=48331619651e3, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=)]
    2022-07-24 oliver169
  3. [GetPortalCommentsPageByObjectIdResponse(id=1878566, encodeId=7a0818e856601, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Fri Dec 16 00:45:58 CST 2022, time=2022-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279824, encodeId=fe3312e98242b, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611675, encodeId=e4ae16116e580, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619651, encodeId=48331619651e3, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1878566, encodeId=7a0818e856601, content=<a href='/topic/show?id=c157696175' target=_blank style='color:#2F92EE;'>#ERS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6961, encryptionId=c157696175, topicName=ERS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e93e105, createdName=anminleiryan, createdTime=Fri Dec 16 00:45:58 CST 2022, time=2022-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279824, encodeId=fe3312e98242b, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1611675, encodeId=e4ae16116e580, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619651, encodeId=48331619651e3, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun Jul 24 15:45:58 CST 2022, time=2022-07-24, status=1, ipAttribution=)]

相关资讯

J Dermatolog Treat:皮肤镜指导下的莫氏显微手术治疗激光后残留基底细胞癌:皮肤镜对手术边缘的划分有帮助吗?

莫氏显微手术(MMS)是治疗基底细胞癌(BCC)的常用技术。在肉眼对肿瘤边缘界定不清的情况下,MMS可能导致需要采取更多的莫氏分期。

Lasers Surg Med:准分子激光治疗斑秃的疗效不劣于皮质类固醇,或是一种有效的替代疗法

斑秃(AA)是一种以非瘢痕性脱发为特征的自身免疫性疾病。尽管斑秃的确切发病机制仍在研究之中,但遗传和自身免疫因素被认为对该疾病有重要影响。皮质类固醇一直是治疗AA的主要手段。

Lasers Med Sci:剥脱性和非剥脱性激光都可有效改善萎缩性痤疮瘢痕

寻常痤疮是一种慢性顽固的皮肤炎症,在青少年甚至成年人中的发病率很高。痤疮疤痕是一种常见的美容并发症,可能会给患者带来生理和心理压力,影响患者的生活质量。

Lasers Med Sci:非热氮等离子体与长脉冲Nd:YAG激光在手部嫩肤中的疗效和安全性

随着新的非侵入性方式的出现,越来越多的人考虑采用整体的身体年轻化方法,来尽量减少面部年轻化与包括手在内的身体其他部位之间的美容差异。

J Dermatolog Treat:激光治疗原发性局部皮肤淀粉样变性的效果如何?

原发性局部皮肤淀粉样变性(PLCA)是一种罕见的慢性疾病,其特征是错误折叠的不溶性淀粉样纤维蛋白聚合物的沉积,其治疗十分具有挑战性。激光治疗是目前治疗各种皮肤病的最受欢迎的方式之一。

J Dermatolog Treat:靶向UVB光疗联合钙泊三醇VS. 单纯靶向UVB治疗银屑病的疗效

银屑病是一种病因复杂的皮肤病,是一种由遗传和环境诱发的慢性、炎症性、免疫介导的全身性疾病。靶向紫外线和外用钙泊三醇经常被用于治疗银屑病,但钙泊三醇和靶向紫外线的联合效果一直存在争议。

Baidu
map
Baidu
map
Baidu
map