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Cell Metab:为何膳食疗法仅对部分人有效?

2015-11-17 佚名 生物谷

为何膳食疗法仅对部分人有效呢?这或许是因为不同个体机体肠道微生物群落和饮食的相互作用不同导致,近日一项刊登在国际杂志Cell Metabolism上的研究报告中,来自哥德堡大学等研究机构的科学家们通过研究发现,摄入大麦面包后血糖可以较好控制的人们或许其肠道微生物菌落也存在一种不同的平衡机制。 饮食干预可以帮助改善人类的机体代谢,同时对于肠道微生物群也有一定影响,此前研究发现在代谢性疾病患者机体中

为何膳食疗法仅对部分人有效呢?这或许是因为不同个体机体肠道微生物群落和饮食的相互作用不同导致,近日一项刊登在国际杂志Cell Metabolism上的研究报告中,来自哥德堡大学等研究机构的科学家们通过研究发现,摄入大麦面包后血糖可以较好控制的人们或许其肠道微生物菌落也存在一种不同的平衡机制。

饮食干预可以帮助改善人类的机体代谢,同时对于肠道微生物群也有一定影响,此前研究发现在代谢性疾病患者机体中存在着肠道微生物群落的改变,比如2型糖尿病等,而且肠道微生物群可以引发肥胖、糖尿病及心血管疾病等疾病。

这项最新研究中,研究者让39名研究对象首先连续三天摄入面粉做成的面包(对照),随后连续三天摄入大麦面包(两种饮食方式间有一定间隔),结果显示,大麦面包可以帮助个体有效改善其血糖,但仅仅对部分个体有效。普氏菌属(Prevotella)细菌被认为和机体高纤维摄入直接相关,相比对饮食干预并无反应的个体而言,普氏菌属存在于大部分对大麦面包有有效反应的个体的机体中;通过将这些个体机体的肠道微生物群转移到无菌小鼠体内后,研究者发现,改变的肠道微生物群落或可促成大麦面包所带来有益效应。

研究者Fredrik Backhed教授表示,我们的研究揭示了肠道微生物群落和饮食之间的相互关联,同时也促进了我们对健康个体机体代谢和疾病的理解,相关研究结果或可帮助解释为何对不同饮食疗法的反应只是对个体有效。加入不同纤维的面包会吸引人们相当大的兴趣,同时也是研究人员重点的研究领域之一,研究者指出,这项研究中我们阐明了肠道微生物群落和多种饮食方式之间的关联,或可帮助我们开发个体化的饮食规则来帮助治疗疾病。

研究者目前计划通过后期的研究来是否肠道微生物可以帮助鉴别对特殊饮食方法有反应的个体,当前的研究结果表明,如果给予小鼠高纤维饮食,那么补充普氏菌属细菌的小鼠机体的血糖或许可以得到较好地改善,同时该研究或许也可以帮助开发普氏菌属细菌和纤维混合的产品来帮助改善机体代谢提供了一定希望。

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    2016-07-13 维他命
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    2016-02-06 guojianrong
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    2016-10-04 一闲
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    2016-09-09 xugumin
  6. [GetPortalCommentsPageByObjectIdResponse(id=1959500, encodeId=5199195950092, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Wed Jul 13 05:52:00 CST 2016, time=2016-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887475, encodeId=3fa0188e47538, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Feb 06 12:52:00 CST 2016, time=2016-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895849, encodeId=e057189584971, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Tue Oct 04 01:52:00 CST 2016, time=2016-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869244, encodeId=af941869244a6, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jun 07 00:52:00 CST 2016, time=2016-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694401, encodeId=51761694401d7, content=<a href='/topic/show?id=988b101054d0' target=_blank style='color:#2F92EE;'>#食疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101054, encryptionId=988b101054d0, topicName=食疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=xugumin, createdTime=Fri Sep 09 18:52:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1350290, encodeId=81271350290b9, content=<a href='/topic/show?id=224a85904ad' target=_blank style='color:#2F92EE;'>#膳食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85904, encryptionId=224a85904ad, topicName=膳食)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Nov 19 03:52:00 CST 2015, time=2015-11-19, status=1, ipAttribution=)]
    2015-11-19 zhaojie88
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