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Obstet Gynecol:超级肥胖孕妇是选择顺产还是剖宫产?

2017-10-22 xing.T MedSci原创

尽管在超级肥胖的孕妇中剖宫产率很高,顺产与降低孕产妇和新生儿的复合发病率相关。临产后需要剖宫产的产妇重症产妇发病率可能更高。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一篇研究文章,研究人员旨在比较顺产与计划剖宫产相比是否与孕产妇和新生儿发病率增加有关。

研究人员对在2008年1月1日和2015年12月31日期间孕周大于34周的分娩时所有身体质量指数(BMI指数)为50或更大的女性进行了回顾性队列研究。多胎妊娠和胎儿畸形的孕妇排除在外。该研究的主要结局为孕产妇和新生儿的发病率。338名妇女的样本量决定了研究周期,并被选定两组之间主要结果发生率差异为30%而具有显著性。调整潜在混杂因素后进行多元logistic回归分析。

在344名满足标准的BMI大于50的女性中,其中201(58%)名孕妇进行顺产,143(42%)名孕妇进行计划剖宫产。顺产孕妇更年轻,为初产妇的可能性更大,既往患有糖尿病的可能性更小。在顺产孕妇中,45%的孕妇改为剖宫产,最常见的原因是分娩停滞(61%)或胎儿状况不良(28%)。即使在调整了年龄、胎次、既往的糖尿病和之前的剖宫产,孕妇的符合产妇和新生儿发病率也有所下降,调整后的比值比为0.42(95%可信区间为0.24-0.75)。在接受剖宫产的孕妇亚组(n=234)中,除了重症产妇发病率在顺产转剖宫产的孕产妇(n=12)中有所增加(8.8% vs. 2.1%,相对风险为4.2,95%可信区间为1.14-15.4)外,计划(n=143)或顺产转剖宫产(n=91)的孕妇和新生儿的发病率并无差异。

尽管在超级肥胖的孕妇中剖宫产率很高,顺产与降低孕产妇和新生儿的复合发病率相关。临产后需要剖宫产的产妇重症产妇发病率可能更高。

原始出处:


Grasch, Jennifer L, et al. Trial of Labor Compared With Cesarean Delivery in Superobese Women.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/publishahead/Trial_of_Labor_Compared_With_Cesarean_Delivery_in.98275.aspx

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    2018-08-01 yhy100200
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    2017-10-22 131****1460

    学习了受益匪浅

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