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Ophthalmol Ther:黄斑毛细血管扩张症2型的治疗综述

2019-04-30 不详 网络

伊朗德黑兰医科大学法拉比眼科医院眼科研究中心的Khodabande A等人近日在Ophthalmol Ther杂志上发表了一篇文章,作者对黄斑毛细血管扩张症2型疾病的治疗现状进行了综述研究。

伊朗德黑兰医科大学法拉比眼科医院眼科研究中心的Khodabande A等人近日在Ophthalmol Ther杂志上发表了一篇文章,作者对黄斑毛细血管扩张症2型疾病的治疗现状进行了综述研究。

黄斑毛细血管扩张症2型(MacTel)是一种相对罕见的疾病,目前没有有效的治疗方法。虽然MacTel以前被认为主要是一种血管疾病,但从其发病机制的研究改变了这一观点,现在认为主要是一种神经退行性疾病。这引起了对该疾病在非增殖期的神经保护治疗方法的改变。

类胡萝卜素补充剂的治疗效果好坏参半。睫状体神经营养因子(CNTF)被认为是一种有希望的治疗手段,但需要进一步研究以确定其实际的治疗效果。在非增殖期中,口服乙酰唑胺观察到一些结构性改善,但没有功能方面的改善。目前对抗血管内皮药物也进行了一些研究,但未发现其在疾病的非增殖期中具有治疗效果,然而发现在继发性新血管形成的治疗中具有显着的结构和功能性改善。

作者总结称,目前对于各种报道的MacTel治疗没有I级证据,仍需要努力进行多中心随机试验以更好地理解这种疾病的潜在治疗方法。

原文出处:

Khodabande, A., et al., Management of Idiopathic Macular Telangiectasia Type 2. Ophthalmol Ther, 2019.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

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    2020-02-04 lsj637
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  5. 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  6. 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createdTime=Thu May 02 10:29:00 CST 2019, time=2019-05-02, status=1, ipAttribution=)]
    2019-05-23 zwjnj2

    努力学习天天学习

    0

  7. 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    2019-05-02 muzishouyi
  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu May 23 08:19:51 CST 2019, time=2019-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1525162, encodeId=0a86152516256, content=<a href='/topic/show?id=65e91031337f' target=_blank style='color:#2F92EE;'>#黄斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103133, encryptionId=65e91031337f, topicName=黄斑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=638b11619344, createdName=muzishouyi, createdTime=Thu May 02 10:29:00 CST 2019, time=2019-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1540410, 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  9. 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createdTime=Thu May 02 10:29:00 CST 2019, time=2019-05-02, status=1, ipAttribution=)]
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