Baidu
map

Gut:粪便中潜血与全因和非结直肠癌死亡率相关

2018-07-18 xing.T MedSci原创

由此可见,可检测到的f-Hb与多种原因引起的死亡风险增加有关。

据报道,可检测的粪便血红蛋白(f-Hb)与结直肠癌(CRC)死亡风险和全因死亡率之间存在关联。近日,消化病领域权威杂志Gut上发表了一篇研究文章,研究人员开始在英国人群中证实或反驳这一观察性结果,并探讨组织粪便潜血试验(gFOBT)阳性结果f-Hb与不同原因死亡之间的关联。

研究人员通过将在2000年3月29日至2016年3月29日期间参与苏格兰泰赛德进行gFOBT筛查的所有受试者(134192)的测试结果(阳性或阴性)与苏格兰国家记录数据库的死亡率数据联系起来,并随访至2016年3月30日。

研究人员发现具有阳性检测结果(n=2714)的受试者死亡风险高于检测结果为阴性的患者:死于CRC:HR为7.79(95%CI为6.13-9.89),p<0.0001(调整了性别、年龄和可能导致出血的药物)以及所有非CRC原因:HR为1.58(95%CI为1.45-1.73),p<0.0001。此外,gFOBT可检测到的f-Hb与死于循环系统疾病、呼吸系统疾病、消化系统疾病(不包括CRC)、神经心理疾病、血液和内分泌疾病以及非CRC疾病的风险增加显著相关。

由此可见,可检测到的f-Hb与多种原因引起的死亡风险增加有关。

原始出处:

Gillian Libby.et al. Occult blood in faeces is associated with all-cause and non-colorectal cancer mortality.Gut. 2018. http://dx.doi.org/10.1136/gutjnl-2018-316483

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1819605, encodeId=5e1f1819605c7, content=<a href='/topic/show?id=6dad9961231' target=_blank style='color:#2F92EE;'>#非结直肠癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99612, encryptionId=6dad9961231, topicName=非结直肠癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Fri Aug 03 06:14:00 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1453142, encodeId=3f0d14531428a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466827, encodeId=d979146682e44, content=<a href='/topic/show?id=edd5e630426' target=_blank style='color:#2F92EE;'>#粪便#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76304, encryptionId=edd5e630426, topicName=粪便)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03cc6863823, createdName=Homburg, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1819605, encodeId=5e1f1819605c7, content=<a href='/topic/show?id=6dad9961231' target=_blank style='color:#2F92EE;'>#非结直肠癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99612, encryptionId=6dad9961231, topicName=非结直肠癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Fri Aug 03 06:14:00 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1453142, encodeId=3f0d14531428a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466827, encodeId=d979146682e44, content=<a href='/topic/show?id=edd5e630426' target=_blank style='color:#2F92EE;'>#粪便#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76304, encryptionId=edd5e630426, topicName=粪便)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03cc6863823, createdName=Homburg, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1819605, encodeId=5e1f1819605c7, content=<a href='/topic/show?id=6dad9961231' target=_blank style='color:#2F92EE;'>#非结直肠癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99612, encryptionId=6dad9961231, topicName=非结直肠癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Fri Aug 03 06:14:00 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1453142, encodeId=3f0d14531428a, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466827, encodeId=d979146682e44, content=<a href='/topic/show?id=edd5e630426' target=_blank style='color:#2F92EE;'>#粪便#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76304, encryptionId=edd5e630426, topicName=粪便)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03cc6863823, createdName=Homburg, createdTime=Fri Jul 20 08:14:00 CST 2018, time=2018-07-20, status=1, ipAttribution=)]
    2018-07-20 Homburg

相关资讯

90%的人都没有看懂的尿常规,原来是这样……

每次拿到体检报告,对于尿常规这项检查结果,你是不是经常被吓到?

Baidu
map
Baidu
map
Baidu
map