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Heart:不是所有人都适合减肥!!!

2017-02-26 xing.T MedSci原创

具有较高BMI的成人先天性心脏病患者具有较低的死亡率。BMI与死亡率之间的相关性在有症状的复杂心脏缺陷患者中特别明显,提示心脏恶病质可能发挥了作用。事实上,在复杂的成人先天性心脏病患者中体重下降与更高的死亡率相关。

异常的体重指数(BMI)与各种心血管疾病较高的死亡率相关。有关成人先天性心脏病患者BMI的预后价值仍未知晓。近日,在心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员的目标是评估成人先天性心脏病患者的BMI分布情况以及其与成人先天性心脏病患者人群症状和生存之间的相关性。

研究人员纳入了3069例成人先天性心脏病患者(平均年龄为32.6岁)并且在2001年至2015年期间一直在研究者所在的医疗机构进行随访。患者根据BMI进行分类,分成体重过轻(BMI<18.5)、正常体重(18.5-25)、超重(25-30)或肥胖(BMI>30),并且对参与者症状、运动能力和死亡率进行了评估。

总体而言,有6.2%的参与者体重过轻,有51.1%的参与者正常体重,28.2%的参与者为超重,14.6%的参与者为肥胖。在单变量Cox分析中,研究人员发现较高的BMI值与较低的全因死亡率和心源性死亡率相关,并且调整年龄、缺陷的复杂性、紫绀和客观运动能力后,这种效应依然存在。较高的BMI与有症状的成人先天性心脏病患者(风险比为0.94(95%可信区间为0.90-0.98),P=0.002)和那些复杂的心脏缺陷患者(风险比为0.96(95%可信区间为0.91-0.997),P=0.048)更好的预后尤为相关。复杂心脏缺陷患者反复进行体重测量,减肥也与较差的生存率相关(风险比为1.82(95%可信区间为1.02-3.24),P=0.04)。

具有较高BMI的成人先天性心脏病患者具有较低的死亡率。BMI与死亡率之间的相关性在有症状的复杂心脏缺陷患者中特别明显,提示心脏恶病质可能发挥了作用。事实上,在复杂的成人先天性心脏病患者中体重下降与更高的死亡率相关。

原始出处:

Margarita Brida,et al. Body mass index in adult congenital heart disease. Heart. 2017. http://dx.doi.org/10.1136/heartjnl-2016-310571

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    2017-02-28 zhaojie88
  2. [GetPortalCommentsPageByObjectIdResponse(id=1356180, encodeId=8a131356180f1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Feb 28 01:25:00 CST 2017, time=2017-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562446, encodeId=23341562446a6, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Feb 28 01:25:00 CST 2017, time=2017-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178136, encodeId=dc521e81360f, content=有意思,有人不适合减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5gJeAA33pg8XSpMyoXQLg4TTWfCC26g4ibkFFUdQVBtofBwAITTWib8S4f1bKDLaYsKVz2KtVfhLQJoia5mISjlibk/0, createdBy=28331949612, createdName=1e10eabem79(暂无匿称), createdTime=Tue Feb 28 00:52:08 CST 2017, time=2017-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178043, encodeId=e2101e804300, content=不是所有的人都适合, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Mon Feb 27 07:09:53 CST 2017, time=2017-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=178032, encodeId=57fc1e8032fc, content=word天,那该怎么办啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Feb 27 00:34:15 CST 2017, time=2017-02-27, status=1, ipAttribution=)]
    2017-02-28 slcumt
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    2017-02-28 1e10eabem79(暂无匿称)

    有意思,有人不适合减肥

    0

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    2017-02-27 老段

    不是所有的人都适合

    0

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    2017-02-27 飛歌

    word天,那该怎么办啊

    0

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