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Clin Implant Dent Relat Res:与正常伤口愈合相比,富含血小板的纤维蛋白并未提高位点保存的新骨形成

2020-09-29 MedSci原创 MedSci原创

富含血小板的纤维蛋白(PRF)可用于牙槽窝位点保存术(ARP),但PRF在位点保存术中的硬组织再生特性尚不清楚。本研究旨在通过组织形态学分析,比较使用PRF作为位点保存材料与正常伤口愈合之间的新骨形成

富含血小板的纤维蛋白(PRF)可用于牙槽窝位点保存术(ARP),但PRF在位点保存术中的硬组织再生特性尚不清楚。本研究旨在通过组织形态学分析,比较使用PRF作为位点保存材料与正常伤口愈合之间的新骨形成比率,研究结果已在线发表于 Clin Implant Dent Relat Res。

征集健康志愿者33名,随机分为PRF组和对照组。进行微创性拔牙。18名患者使用PRF进行ARP治疗,其余患者则任其自然愈合。牙齿拔除后2个月使用曲华ine bur采集骨标本。使用软件Fiji Is Just Image J(版本2,GNU General Public License)对新骨形成面积与总牙槽窝面积进行组织形态分析。

 

结果,共有33名志愿者参加。采集了28个骨标本。PRF组的新骨形成率高于对照组(分别为31.33±18%和26.33±19.63%)。然而,PRF组和对照组之间的比值没有统计学上的显著差异(P = .431)。

 

综上所述,该研究结果表明,与正常伤口愈合相比,PRF在ARP中的使用对拔牙后的新骨形成没有统计学意义(P > .05)。

 

原始出处:

 

Kanokporn AreewongMontri ChantaramungkornPathawee Khongkhunthian. Platelet-rich fibrin to preserve alveolar bone sockets following tooth extraction: A randomized controlled trial. Clin Implant Dent Relat Res. 2019 Dec;21(6):1156-1163. doi: 10.1111/cid.12846.

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    2020-12-19 xuyu
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    2021-05-28 xuyong536
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