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Int J Gynaecol Obstet:二氧化碳激光治疗可有效改善绝经后女性外阴阴道萎缩的症状

2022-08-14 MedSci原创 MedSci原创

外阴阴道萎缩(VVA),也被称为更年期泌尿生殖系统综合征,是一种发生在绝经后妇女身上的疾病,临床表现为症状包括阴道灼热、干燥、瘙痒、排尿困难和下尿路功能障碍。

外阴阴道萎缩(VVA),也被称为更年期泌尿生殖系统综合征,是一种发生在绝经后妇女身上的疾病,临床表现为症状包括阴道灼热、干燥、瘙痒、排尿困难和下尿路功能障碍。据报道,大约50%的绝经后妇女至少有一种症状,这可能对妇女的性功能和生活质量(QoL)产生不利影响。近日,发表于Int J Gynaecol Obstet的一项研究探讨了二氧化碳激光治疗绝经后妇女外阴萎缩的疗效。

研究人员检索了PubMed、Embase、Cochrane图书馆和Web of Science数据库中2020年6月9日之前收录的关于二氧化碳激光治疗绝经后妇女外阴萎缩疗效的前瞻性研究。两名研究人员独立审查了文章并提取了数据。对每个结果指标进行了异质性检验。在所有模型中都进行了敏感性分析。

结果,研究共纳入了12篇文章,包括459名参与者。分析结果显示,与基线相比,二氧化碳激光治疗后患者阴道健康指数(VHIs)在1、3、6和12个月的随访中明显升高(P<0.001)。对于VVA的严重程度,在1、3、6和12个月随访中的阴道干燥的视觉模拟量表评分(P<0.050),1个月随访中的阴道灼热、瘙痒和排尿困难(P<0.001),以及1、3、6和12个月随访中的排尿困难(P<0.001)都明显降低。在FSFI方面,1个月、3个月、6个月和12个月随访时的总分(P<0.001),以及1个月随访时的欲望、唤醒、润滑、高潮、满意度和疼痛方面的得分(P<0.050)都明显较高。在生活质量方面,PCS12和MCS12的得分在1个月的随访中都明显较高(P < 0.050)。

综上所述,该研究结果表明,二氧化碳激光治疗可能对有VVA症状的绝经后妇女有效,可以改善其生活质量和性功能。

 

原始出处:

Meichen Liu, et al., Efficacy of CO 2 laser treatment in postmenopausal women with vulvovaginal atrophy: A meta-analysis. Int J Gynaecol Obstet. 2022 Aug;158(2):241-251.  doi: 10.1002/ijgo.13973.  

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    2022-08-28 chendoc252
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    2022-12-09 yhy100200
  5. 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    2022-08-14 zwddoctor

    近日,发表于Int J Gynaecol Obstet的一项研究探讨了二氧化碳激光治疗绝经后妇女外阴萎缩的疗效

    0

  6. 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    2022-08-09 oliver169
  8. 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    2022-08-09 ewsr3
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