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J Investig Clin Dent:益生菌辅助应用是否有益于牙周治疗效果

2018-04-05 MedSci MedSci原创

本研究旨在评估益生菌作为治疗慢性牙周炎(CP)中洁治和根面平整(SRP)的辅助效果。这项研究的焦点问题是:与安慰剂/无治疗组相比,益生菌的辅助使用可以在治疗CP时产生更好的临床牙周结果?电子和手册文献检索2017年12月前以下数据库收录的相关文章:MEDLINE,EMBASE,Cochrane对照试验中心注册和Cochrane口腔健康组试验注册。计算加权平均差异(WMD)和95%置信区间(CI)。

本研究旨在评估益生菌作为治疗慢性牙周炎(CP)中洁治和根面平整(SRP)的辅助效果。这项研究的焦点问题是:与安慰剂/无治疗组相比,益生菌的辅助使用可以在治疗CP时产生更好的临床牙周结果?

电子和手册文献检索2017年12月前以下数据库收录的相关文章:MEDLINE,EMBASE,Cochrane对照试验中心注册和Cochrane口腔健康组试验注册。计算加权平均差异(WMD)和95%置信区间(CI)。

结果共纳入了七项临床研究。四项研究表明在减少牙周探诊深度(PPD)和临床附着水平(CAL)获得方面有额外的益处,而三项研究显示益生菌和SRP/安慰剂之间的临床牙周结果相当。研究发现PPD降低和CAL增益存在明显的异质性。随访时,益生菌与安慰剂/SRP之间的CAL增加的整体平均差异明显(WMD = 1.41,95%CI = 0.15-2.67,P = .028)。

综上所述,该研究结果表明,辅助益生菌使用可以在CP中获得额外的益处。尽管如此,还需要进一步开展高质量的微生物学结果随机临床试验,以获得这方面的有力结论。

原始出处:

Ikram S, Hassan N, et al., Systematic review and meta-analysis of double-blind, placebo-controlled, randomized clinical trials using probiotics in chronic periodontitis. J Investig Clin Dent. 2018 Mar 31:e12338. doi: 10.1111/jicd.12338.

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    2018-04-07 liuyong2982
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    2018-04-05 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1894047, encodeId=3049189404e31, content=<a href='/topic/show?id=5e456463eee' target=_blank style='color:#2F92EE;'>#治疗效果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64637, encryptionId=5e456463eee, topicName=治疗效果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=373a131, createdName=jxrzshh, createdTime=Sun Jan 20 18:49:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051113, encodeId=6b412051113a2, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu Sep 27 11:49:00 CST 2018, time=2018-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450861, encodeId=4258145086145, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Apr 07 06:49:00 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493522, encodeId=95341493522bd, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Sat Apr 07 06:49:00 CST 2018, time=2018-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031710, encodeId=0abc1031e10cb, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Thu Apr 05 18:49:00 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303041, encodeId=80e130304188, content=学习了.长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Apr 05 17:38:31 CST 2018, time=2018-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=303022, encodeId=e46c30302203, content=优质资源.共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Thu Apr 05 16:37:48 CST 2018, time=2018-04-05, status=1, ipAttribution=)]
    2018-04-05 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-04-05 虈亣靌

    优质资源.共同学习

    0

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