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Lancet:谨慎连续怀孕之间的体重变化,可导致死产和婴儿死亡

2015-12-03 崔倩 译 MedSci原创

孕妇超重和肥胖是死产和婴儿死亡的危险因素。孕妇体重随时间的变化是否影响这些风险目前尚不清楚。该研究的目的是评估第一次和第二次怀孕之间BMI的变化是否会影响第二个后代的死产率和婴儿死亡率。

孕妇超重和肥胖是死产和婴儿死亡的危险因素。孕妇体重随时间的变化是否影响这些风险目前尚不清楚。该研究的目的是评估第一次和第二次怀孕之间BMI的变化是否会影响第二个后代的死产率和婴儿死亡率。

在一项以瑞典人群为基础的队列研究中,参与者在1992年1月1日和2012年12月31号之间生下了她们的第一个和第二个孩子,研究人员调查了从第一到第二次怀孕妊娠早期身体质量指数(BMI)的变化与第二次怀孕后死胎和婴儿死亡风险之间的关联。根据BMI变化类别的每个结果的相对危险(RR),是采用二项回归计算的。

在研究期间,587710名女性中的456711名(77.7%)生下了第一个和第二个单胎,并且有完整可用的信息。与那些在两次怀孕之间有稳定BMI女性(在−1kg/m2和<1kg/m2之间变化)相比,那些在两次怀孕之间BMI增加了至少4kg/m2的女性调整后的死胎RR为1.55(95%Cl 1.23至1.96),婴儿死亡的RR为1.29(1.00至1.67)。死胎的风险随着BMI的增加呈线性增加。

第一次怀孕时有健康的BMI的女性(<25kg/m2)在第二次怀孕时,婴儿死亡率的风险只随着BMI的增加而增加;那些健康体重的女性BMI增加2kg/m2以上但小于4kg/m2的,调整后的RR为1.27(1.01至1.59),那些增加4kg/m2以上的女性调整后的RR为1.60(1.16至2.22)。在超重女性中(体BMI≥25kg/m2),怀孕前减肥降低了新生儿死亡的风险。

该研究结果强调有必要防止那些健康和超重的女性在怀孕之前体重增加,超重的女性应该进行减肥来减低风险。

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    2016-01-21 howi
  4. [GetPortalCommentsPageByObjectIdResponse(id=2079407, encodeId=afeb20e940742, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Wed Dec 09 10:24:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1814168, encodeId=883c181416803, content=<a href='/topic/show?id=963794553f7' target=_blank style='color:#2F92EE;'>#连续怀孕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94553, encryptionId=963794553f7, topicName=连续怀孕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Sat Mar 05 17:24:00 CST 2016, time=2016-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828330, encodeId=69c718283306f, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Jan 21 07:24:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49115, encodeId=9beb491157f, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49116, encodeId=ca9749116d5, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45418, encodeId=90ff45418e5, content=谢谢啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 10 09:01:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583389, encodeId=2ff915833893c, content=<a href='/topic/show?id=12fb6339120' target=_blank style='color:#2F92EE;'>#死产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63391, encryptionId=12fb6339120, topicName=死产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c43916977494, createdName=小小小向日葵, createdTime=Fri Dec 04 23:24:00 CST 2015, time=2015-12-04, status=1, ipAttribution=)]
    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

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    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2079407, encodeId=afeb20e940742, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Wed Dec 09 10:24:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1814168, encodeId=883c181416803, content=<a href='/topic/show?id=963794553f7' target=_blank style='color:#2F92EE;'>#连续怀孕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94553, encryptionId=963794553f7, topicName=连续怀孕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Sat Mar 05 17:24:00 CST 2016, time=2016-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828330, encodeId=69c718283306f, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Jan 21 07:24:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49115, encodeId=9beb491157f, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49116, encodeId=ca9749116d5, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45418, encodeId=90ff45418e5, content=谢谢啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 10 09:01:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583389, encodeId=2ff915833893c, content=<a href='/topic/show?id=12fb6339120' target=_blank style='color:#2F92EE;'>#死产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63391, encryptionId=12fb6339120, topicName=死产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c43916977494, createdName=小小小向日葵, createdTime=Fri Dec 04 23:24:00 CST 2015, time=2015-12-04, status=1, ipAttribution=)]
    2015-12-10 cmn

    谢谢啦

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2079407, encodeId=afeb20e940742, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Wed Dec 09 10:24:00 CST 2015, time=2015-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1814168, encodeId=883c181416803, content=<a href='/topic/show?id=963794553f7' target=_blank style='color:#2F92EE;'>#连续怀孕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94553, encryptionId=963794553f7, topicName=连续怀孕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Sat Mar 05 17:24:00 CST 2016, time=2016-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828330, encodeId=69c718283306f, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Thu Jan 21 07:24:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49115, encodeId=9beb491157f, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49116, encodeId=ca9749116d5, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:07:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45418, encodeId=90ff45418e5, content=谢谢啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 10 09:01:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583389, encodeId=2ff915833893c, content=<a href='/topic/show?id=12fb6339120' target=_blank style='color:#2F92EE;'>#死产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63391, encryptionId=12fb6339120, topicName=死产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c43916977494, createdName=小小小向日葵, createdTime=Fri Dec 04 23:24:00 CST 2015, time=2015-12-04, status=1, ipAttribution=)]
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