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晚期乳腺癌：诺华公司的PI3K抑制剂Piqray获FDA授权

2019-05-25 不详 网络

PI3K抑制剂晚期乳腺癌Piqray
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诺华公司近日宣布，FDA批准了Piqray（alpelisib）与Faslodex（氟维司群）联合用于HR阳性、HER2阴性、PIK3CA突变的晚期或转移性乳腺癌患者（患者包括女性和男性），这些患者在基于内分泌的治疗方案后出现疾病进展。

诺华公司近日宣布，FDA批准了Piqray（alpelisib）与Faslodex（氟维司群）联合用于HR阳性、HER2阴性、PIK3CA突变的晚期或转移性乳腺癌患者（患者包括女性和男性），这些患者在基于内分泌的治疗方案后出现疾病进展。FDA药物评估和研究中心血液学和肿瘤学产品办公室主任Richard Pazdur评论道：“Piqray是第一种在治疗这类乳腺癌患者方面具有临床意义的PI3K抑制剂”。

这项批准得到了SOLAR-1试验的数据支持，该研究招募了572例符合要求的患者。在去年10月公布的研究结果中，与单独使用Faslodex相比，将Piqray添加到Faslodex可将死亡或疾病进展的风险降低35％。


原始出处：

http://www.firstwordpharma.com/node/1643129#axzz5ovUpnHnX

本文系梅斯医学（MedSci）原创编译整理，转载需授权!

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    2019-10-30 仁医06

    #Piqray#

    0

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    2020-05-10 jklm09

    #抑制剂#

    0

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    2019-05-27 nian.wang1982

    #诺华#

    0

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    2019-05-27 ms1292405679162969

    #PI3K#

    0

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    2019-05-27 bbjsj_1983

    #PI3K抑制剂#

    0

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