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Int J Impot Res:阴茎勃起功能障碍病人中潜在的结核感染研究

2017-12-06 AlexYang MedSci原创

关于在阴茎勃起功能障碍病人中潜在的结核感染(LTBI)流行度以及它通过慢性炎症诱导的动脉粥样硬化过程而对高等级ED的贡献方面的调查研究到目前为止还没有。最近,有研究人员确定了在阴茎勃起功能障碍病人群体中LTBI的频率,并且探索了LTBI对高等级ED的贡献情况。对所有的研究样本,研究人员进行了临床评估、成像研究和实验室调查。评估包括但不仅限于经阴囊超声、结核菌素皮试和QuantiFERON-TB G

关于在阴茎勃起功能障碍病人中潜在的结核感染(LTBI)流行度以及它通过慢性炎症诱导的动脉粥样硬化过程而对高等级ED的贡献方面的调查研究到目前为止还没有。最近,有研究人员确定了在阴茎勃起功能障碍病人群体中LTBI的频率,并且探索了LTBI对高等级ED的贡献情况。

对所有的研究样本,研究人员进行了临床评估、成像研究和实验室调查。评估包括但不仅限于经阴囊超声、结核菌素皮试和QuantiFERON-TB Gold测试。研究样本的平均年龄为47.9±13.6岁。研究发现,大于30%的病人患有LTBI,43%的病人患有高等级ED。在多变量分析中,研究发现,与低等级ED对比,较大的年龄(不小于40岁)(OR, 5.2; 95% CI, 1.9-54.6; p 0.004)、代谢综合症(MS)(OR, 3.4; 95% CI, 1.3-48.2; p 0.016)和LTBI(OR, 4.1; 95% CI, 1.7-61.3; p 0.021)与高等级ED显著地、独立地相关。总之,LTBI在高等级ED病人中的流行度要比那些低等级ED病人中的更高。除了LTBI,与低等级ED与相比,较大的年龄和MS与高等级ED相关。

原始出处:

Ahmad F. A. Hasanain, Ali M. A. Mahran, Ahmed S. Safwat et al. Latent tuberculosis infection among patients with erectile dysfunction. Int J Impot Res. 01 Dec 2017.

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    2018-10-02 habb
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1771139, encodeId=a5f11e711394f, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Tue Oct 02 10:12:00 CST 2018, time=2018-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721513, encodeId=d3631e21513a4, content=<a href='/topic/show?id=12cae864776' target=_blank style='color:#2F92EE;'>#结核感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78647, encryptionId=12cae864776, topicName=结核感染)], attachment=null, authenticateStatus=null, createdAvatar=null, 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Dec 08 13:12:00 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575071, encodeId=a85e15e5071ec, content=<a href='/topic/show?id=6f66121e89e' target=_blank style='color:#2F92EE;'>#MPO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12178, encryptionId=6f66121e89e, topicName=MPO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7b9016060451, createdName=风铃826, createdTime=Fri Dec 08 13:12:00 CST 2017, time=2017-12-08, status=1, ipAttribution=)]
    2017-12-08 dingxiaobo
  6. 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  7. 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    2017-12-08 风铃826

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Int J Impot Res:肌生成抑制蛋白,一种纤维化因子和横纹肌群的主要抑制子,存在于阴茎和血管平滑肌中

肌生成抑制蛋白在平滑肌细胞(SMC)中存在于有条纹的肌纤维中(除了肌层细胞)中还未报道。最近,研究人员在小鼠中调查了是否肌生成抑制蛋白存在于阴茎的SMC中和血管壁中,如果存在,肌生成抑制蛋白是否转录表达并且与某几种形式的勃起功能障碍(ED)的海绵体SMC的缺失有关,研究人员对其进行了探究。研究人员利用免疫组化技术或者荧光技术和蛋白免疫印迹技术,在会阴横纹肌、阴茎海绵体的SMC、动脉和静脉以及主动脉

治疗前列腺肥大竟可导致勃起功能障碍

治疗前列腺肥大竟可导致勃起功能障碍患有良性前列腺肥大的男性,使用非那雄胺(也成为保列治或保法止)治疗可加重勃起功能障碍(ED)。此外,使用非那雄胺治疗前列腺肥大还可引起男性睾酮水平的下降导致男性性腺功能减退(没有性激素因此无法生育)。然而,使用坦索罗辛治疗前列腺肥大的男性却不存在这些问题。该研究由波士顿大学医学院领导进行,其研究结果在线发表于<激素分子生物学和临床研究杂志>。关于5α还

Sci Rep:代谢综合征与勃起功能障碍有关!

代谢综合征(MetS)是勃起功能障碍(ED)的一个风险因子,但是潜在的机制仍旧不清楚。最近,有研究人员进行了旨在确定代谢综合征相关ED(MED)的潜在机制。研究人员对Sprague Dawley(SD)大鼠进行了为期6个月的高脂肪喂养,之后对其进行了代谢参数的评估,并且进行了阿朴吗啡测试来确定MED。另外,研究人员只对那些患有MED的大鼠进行为期4周的表皮生长因子(EGF)或者媒介物的阴茎注射,并

2016勃起功能障碍中西医结合诊疗指南(试行版)发布

本指南参照英国牛津大学循证医学中心对循证级别提出的分类方法,参考国内外最新指南及研究成果制定,具有以下特点:①西医部分内容参考国内外最新指南和权威期刊文献,体现本指南内容的新颖性、科学性和指导性;②中医部分内容参考经典文献、教材和专著,保证指南内容的准确性、统一性;③国内众多知名中西医结合男科专家参与编写和讨论,确保指南的权威性、实用性和可操作性。全文获取:下载地址:指南下载 (需要扣积

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