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Sci Rep:用Meltpro TB实验快速诊断耐多药结核病与超级耐多药结核病

2016-11-20 xing.T MedSci原创

总的来说,Meltpro TB实验已经证实在检测出耐多药结核病以及超级耐多药结核病的良好性能,其灵敏度分别为86.7%和71.4%。在中国Meltpro TB是可以作为一种检测耐多药结核病和超级耐多药结核病的优良替代检测方法,与其他检测实验相比,具有精度高、测试时间短、单价低的特点。

新的诊断方法提供了一种很有前途的解决方案来快速和可靠地检测出耐药结核菌株。近日,来自中国疾病预防控制中心国家结核病预防控制中心的研究人员在Scientific Reports杂志上发表其团队的研究成果,旨在评估用Meltpro TB实验通过检测患者痰标本确定耐多药结核病和超级耐多药结核病患者的检验效能。

研究人员采用2057例痰涂片阳性的肺结核患者痰标本进行Meltpro TB实验,用960型结核分枝杆菌生长指示管(MGIT)进行的药敏试验结果作为参考标准。研究人员发现该Meltpro TB实验检测出耐利福平结核杆菌的灵敏度为94.2%,检测出耐异烟肼结核杆菌的灵敏度为84.9%。对于耐二线治疗药物的结核杆菌,研究人员发现该实验检测出耐氧氟沙星结核杆菌的灵敏度为83.3%,检测出耐丁胺卡那霉素的结核杆菌灵敏度为75%,以及检测出耐卡那霉素结核杆菌灵敏度为63.5%。然而,该实验在检测耐卡那霉素结核杆菌灵敏度检测方面,在国内两个不同地区其灵敏度存在显著的差异,在广东为53.2%,而在山东为81.5%(P=0.015 )。

总的来说,Meltpro TB实验已经证实在检测出耐多药结核病以及超级耐多药结核病方面的良好性能,其灵敏度分别为86.7%和71.4%。在中国Meltpro TB是可以作为一种检测耐多药结核病和超级耐多药结核病的优良替代检测方法,与其他检测实验相比,具有精度高、测试时间短、单价低的特点。

原始出处:

Pang Y, et al. Rapid diagnosis of MDR and XDR tuberculosis with the MeltPro
TB assay in China
. Sci Rep. 2016 May 6;6:25330. doi: 10.1038/srep25330.

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    2016-11-22 sunylz
  4. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-22 母鸡

    很好学习并分享结核诊断的最新资料

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 susice

    收藏了,学习下

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 flysky120

    谢谢学习一下知识

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 为你把脉

    吃饭古古怪怪呵呵哈哈哈

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 1e131038m59(暂无匿称)

    讲的真好,学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 huaning

    很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1254020, encodeId=3c23125402011, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458398, encodeId=d7341458398b7, content=<a href='/topic/show?id=a39f803557a' target=_blank style='color:#2F92EE;'>#耐多药结核病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80355, encryptionId=a39f803557a, topicName=耐多药结核病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa6e6064686, createdName=mgqwxj, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601821, encodeId=b2221601821b7, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Nov 22 13:50:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157410, encodeId=0b8115e410f0, content=很好学习并分享结核诊断的最新资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161018/IMG5805DF28A2E158499.jpg, createdBy=223f1967572, createdName=母鸡, createdTime=Tue Nov 22 09:05:57 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157236, encodeId=171215e23670, content=收藏了,学习下, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Nov 21 09:55:14 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157205, encodeId=a5a715e2051a, content=谢谢学习一下知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Nov 21 08:26:15 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157193, encodeId=637c15e19346, content=吃饭古古怪怪呵呵哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon Nov 21 08:05:04 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157189, encodeId=de0615e18957, content=讲的真好,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e7f41959343, createdName=1e131038m59(暂无匿称), createdTime=Mon Nov 21 07:54:40 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157188, encodeId=f52915e1887b, content=很多病原研究已被多数医务人员轻视,但这些研究还是很重要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1cf61629238, createdName=huaning, createdTime=Mon Nov 21 07:44:28 CST 2016, time=2016-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157187, encodeId=7ff615e1873c, content=好东西, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161008/IMG57F86839881C22340.jpg, createdBy=38251962317, createdName=后宫三千, createdTime=Mon Nov 21 07:33:47 CST 2016, time=2016-11-21, status=1, ipAttribution=)]
    2016-11-21 后宫三千

    好东西

    0

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