2009 EFNS神经病理性疼痛的评估指南（2009修订版）

中文标题：

2009 EFNS神经病理性疼痛的评估指南（2009修订版）

英文标题：

EFNS guidelines on neuropathic pain assessment: revised 2009

发布机构：

欧洲神经科学协会联盟

发布日期：

2010-03-08

简要介绍：

Background and purpose: We have revised the previous EFNS guidelines on neuropathicpain (NP) assessment, which aimed to provide recommendations for thediagnostic process, screening tools and questionnaires, quantitative sensory testing(QST), microneurography, pain-related reflexes and evoked potentials, functionalneuroimaging and skin biopsy.Methods: We have checked and rated the literature published in the period 2004–2009, according to the EFNS method of classification for diagnostic procedures.Results: Most of the previous recommendations were reinforced by the new studies.The main revisions relate to: (i) the new definition of NP and a diagnostic gradingsystem; (ii) several new validated clinical screening tools that identify NP components,and questionnaires which assess the different types of NP; (iii) recent high-qualitystudies on laser-evoked potentials (LEPs) and skin biopsy.Conclusions: History and bedside examination are still fundamental to a correctdiagnosis, whilst screening tools and questionnaires are useful in indicating probableNP; QST is also useful for indicating the latter, and to assess provoked pains andtreatment response. Amongst laboratory tests, LEPs are the best tool for assessing Adpathway dysfunction, and skin biopsy for assessing neuropathies with distal loss ofunmyelinated nerve fibres.