CPIC药物遗传学指导华法林使用剂量指南（2017年更新）

2017-02-17 临床药物基因组学实施联盟 Clin Pharmacol Ther. 2017 Feb 15. doi: 10.1002/cpt

This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published l

中文标题：

英文标题：

Clinical pharmacogenetics implementation consortium cpic guideline for pharmacogenetics-guided warfarin dosing: 2017 update.

发布机构：

临床药物基因组学实施联盟

发布日期：

2017-02-17

简要介绍：

This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for CYP2C9, VKORC1, CYP4F2, and rs12777823 genotype-guided warfarin dosing to achieve a target international normalized ratio of 2-3 when clinical genotype results are available. In addition, this updated guideline incorporates recommendations for adult and pediatric patients that are specific to continental ancestry.

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