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2020 CPIC指南:CYP2C9和非甾体类抗炎药

2020-03-19 临床药物基因组学实施联盟 Clin Pharmacol Ther. 2020 Mar 19.

2020年3月,临床药物基因组学实施联盟(CPIC)发布了CYP2C9和非甾体类抗炎药指南,非甾体类抗炎药(NSAIDs) 是最长应用的止痛药之一,临床应用可能引起严重胃肠道、肾脏以及心血管不良事件。

中文标题:

2020 CPIC指南:CYP2C9和非甾体类抗炎药

英文标题:

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and Nonsteroidal Anti-inflammatory Drugs.

发布日期:

2020-03-19

简要介绍:

2020年3月,临床药物基因组学实施联盟(CPIC)发布了CYP2C9和非甾体类抗炎药指南,非甾体类抗炎药(NSAIDs) 是最长应用的止痛药之一,临床应用可能引起严重胃肠道、肾脏以及心血管不良事件。CYP2C9多态性影响这类药物的代谢和清除,从而影响药物暴露和潜在安全性。本文主要提供了基于CYP2C9基因型的NSAIDs应用建议。

 

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