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益母草注射液防治产后出血的应用共识(2017)

2017-10-30 妇产科相关专家组(统称) 中国实用妇科与产科杂志.2017,33(10):1053-1056.

产后出血发生率居高不下是我国孕产妇死亡的重要原因,子宫收缩乏力是造成产后出血的首要因素,应用快速、安全、有效的子宫收缩剂仍是产科医生处理宫缩乏力的根本手段。目前临床应用的宫缩剂包括垂体后叶素类、前列腺素类和生物碱类,其中缩宫素最为常用,缩宫素虽起效快,但半衰期短、有受体饱和现象、对子宫下段平滑肌作用弱。而源于“经产良药”益母草(Leonurus japonicas Houtt)的现代化纯中药制剂益

中文标题:

益母草注射液防治产后出血的应用共识(2017)

发布日期:

2017-10-30

简要介绍:

产后出血发生率居高不下是我国孕产妇死亡的重要原因,子宫收缩乏力是造成产后出血的首要因素,应用快速、安全、有效的子宫收缩剂仍是产科医生处理宫缩乏力的根本手段。目前临床应用的宫缩剂包括垂体后叶素类、前列腺素类和生物碱类,其中缩宫素最为常用,缩宫素虽起效快,但半衰期短、有受体饱和现象、对子宫下段平滑肌作用弱。而源于“经产良药”益母草(Leonurus japonicas Houtt)的现代化纯中药制剂益母草注射液(Motherwort injection)与缩宫素等缩宫剂具有协同互补作用,可促进全子宫平滑肌收缩,无受体饱和现象;其缩宫作用的主要有效化学成分是益母草生物碱等。临床广泛应用于预防和治疗产后出血,其基础药理、临床有效性和安全性已被较多研究验证并在临床应用中得到广泛认可。虽临床已应用多年,但临床使用方法不甚规范。基于此,国内围产医学、临床药学、循证医学和各临床相关学科的专家共同起草和制定了《益母草注射液防治产后出血的应用共识》,以供医师、药师在临床工作中参考,进一步规范益母草注射液的临床应用,以期取得更理想的效果,使更多的患者受益。

 

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    重要原因.子宫收缩乏力是造成产后出血的首要因素.应用快速.安全.有效的子宫收缩剂仍是产科医生处理宫缩乏力的根本手段.

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