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Advances in Adrenal and Extra-adrenal Paraganglioma: Practical Synopsis for Pathologists

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (1)

Adrenal paraganglioma (or pheochromocytoma) and extra-adrenal paraganglioma, collectively abbreviated PPGL, are rare but spectacular nonepithelial neu......

Pathologic Diagnosis of Well-differentiated Hepatocellular Lesions: A Practical Approach to Diagnosis With Particular Focus in Core Needle Biopsies and Utilization of Ancillary Techniques

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (5)

Common well-differentiated hepatocellular lesions include focal nodular hyperplasia, focal nodular hyperplasia-like lesions, large regenerative nodule......

Update on the Use of Molecular Subtyping in Breast Cancer

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (6)

The standard of care for invasive cancers of the breast has been and continues to be to evaluate them for breast prognostic markers: estrogen receptor......

Histopathologic Features of Adrenal Cortical Carcinoma

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (1)

Adrenal cortical carcinoma (ACC) is a rare and aggressive malignancy that poses challenging issues regarding the diagnostic workup. Indeed, no presurg......

Role of Surgical Pathologist for Detection of Immunooncologic Predictive Factors in Head and Neck Cancer

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (3)

Immunotherapy has shown promising results in the treatment of recurrent and metastatic head and neck cancers. Antiprogrammed cell death (PD)-1 therapi......

Pathology of Immunotherapy-induced Responses in Cutaneous Melanoma: Current Evidences and Future Perspectives

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (3)

Over the last years, immune checkpoint inhibitors (ICIs) have demonstrated remarkable anti-tumor activity and beneficial effects in patients with earl......

Neuroendocrine Neoplasms of the Pancreas: Diagnostic Challenges and Practical Approach

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (1)

Most pancreatic neuroendocrine neoplasms are slow-growing, and the patients may survive for many years, even after distant metastasis. The tumors usua......

Immune-Checkpoint-Inhibitor Therapy-Principles and Relevance of Biomarkers for Pathologists and Oncologists

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (3)

Immune-checkpoint-inhibitor (ICI) therapy has been one of the major advances in the treatment of a variety of advanced or metastatic tumors in recent ......

The Significance of Recognition of Human Epidermal Growth Factor 2 Low in Breast Cancer Therapy

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (6)

In response to recent clinical trials that demonstrate the clinical benefit of antibody-drug conjugate drug therapy in breast cancer (BC) with human e......

IDH2-Mutated Sinonasal Tumors: A Review

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (2)

Introduction:Genetic profiling has caused an explosion in the subclassification of sinonasal malignancies. Distinguishing several of these tumor types......

Nipple Lesions of the Breast An Update on Morphologic Features, Immunohistochemical Findings and Differential Diagnosis

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (6)

Because of the unique anatomic structure of the nipple, a few specific breast lesions occur only at this site. Large lactiferous sinuses may be involv......

Follicular Neoplasm of Thyroid Revisited: Current Differential Diagnosis and the Impact of Molecular Testing

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (1)

The diagnosis of follicular neoplasm (FN) in thyroid cytopathology has a long history that originated not long after the practice of fine-needle aspir......

The Spectrum of Digestive Tract Histopathologic Findings in the Setting of Severe Acute Respiratory Syndrome Coronavirus-2 Infection: What Pathologists Need to Know

期刊: ADVANCES IN ANATOMIC PATHOLOGY, 2023; 30 (5)

Although the novel severe acute respiratory syndrome coronavirus-2 is known primarily to affect the respiratory system, current evidence supports its ......

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