期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 324 (5)
The thick ascending limb (TAL) is critical for renal control of fluid and ion homeostasis. The function of the TAL depends on the activity of the bume......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (4)
Glycolytic overload in diabetes causes large accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO) and overproduction of advance......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (5)
Hypoxia and oxidative stress are considered to be underlying factors in the deterioration of renal function and pathogenesis in acute kidney injury (A......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (3)
Renal sympathetic innervation is important in the control of renal and systemic hemodynamics and is a target for pharmacological and catheter-based th......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (6)
Blood pressure (BP) responses to sodium intake show great variation, discriminating salt-sensitive (SS) from salt-resistant (SR) individuals. The path......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (4)
In recent years, biology and precision medicine have benefited from major advancements in generating large-scale molecular and biomedical datasets and......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 324 (4)
Postoperative acute kidney injury (AKI) is a common complication after surgery. The pathophysiology of postoperative AKI is complex. One potentially i......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (5)
Patients with chronic kidney disease (CKD) are at increased risk of cardiovascular disease. This increased risk cannot be fully explained by tradition......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (5)
Hypoxia and oxidative stress are considered to be underlying factors in the deterioration of renal function and pathogenesis in acute kidney injury (A......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (5)
The transmembrane protein SLC22A17 [or the neutrophil gelatinase-associated lipocalin/lipocalin-2 (LCN2)/24p3 receptor] is an atypical member of the S......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 324 (3)
Sex differences in renal function and blood pressure have been widely described across many species. Blood pressure dips dur-ing sleep and peaks in th......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 324 (1)
Although mesangial cell-glomerular basement membrane (GBM) connections play a key role in maintaining the glomerular capil-lary loop structure, inform......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (6)
Neuropilin 1 (NRP1) is a single-channel transmembrane glycoprotein whose role and mechanism in renal fibrosis remain incompletely elucidated. Therefor......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 324 (3)
Mg2+ is essential for many cellular and physiological processes, including muscle contraction, neuronal activity, and metabo-lism. Consequently, the b......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2023; 325 (1)
Heart failure with preserved ejection fraction (HFpEF) is characterized by obesity, hypertension, diabetes mellitus, and chronic kidney disease. Obese......