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Exogenous glutamine ameliorates diabetic nephropathy in a rat model of type 2 diabetes mellitus through its antioxidant and anti-inflammatory activities

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (2)

This study aimed to evaluate the effects of glutamine (Gln) on diabetic nephropathy and other complications in a rat model of type 2 diabetes mellitus......

Positive effects of leaves of Erodium glaucophyllum on lipid peroxidation and antioxidant defence depletion induced by obesity

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (1)

Medicinal plants are sources of natural antioxidants thanks to their secondary metabolites. Previous studies showed that administration of Erodium gla......

Andrographis paniculata (Burm. f.) Nees extract ameliorates insulin resistance in the insulin-resistant HepG2 cells via GLUT2/IRS-1 pathway

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; ()

Hyperglycaemia is one condition related to inflammation leading to insulin signalling impairment. This study was conducted to investigate the insulin ......

Reverse pharmacology approach to validate the diabetic wound-healing activity of Jatyadi thailam formulations in vitro on diabetic mimic environment

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; ()

Objective: Jatyadi thailam, an Ayurvedic preparation, is renowned for its efficacy in diabetic wound healing and inflammation. This study aimed to val......

Reverse expression pattern of sirtuin-1 and histone deacetylase-9 in coronary artery disease

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (1)

Background SIRT1andHDAC9 genes are related to inflammation and may contribute to the pathogenesis of coronary artery disease (CAD). We aimed to evalua......

The effect of 4-week endurance training on serum levels of irisin and betatrophin in streptozotocin- induced diabetic rats

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (3)

Betatrophin known as pancreatic beta-cell proliferation marker is secreted as a result of the muscle irisin's expression induced by exercise. The pres......

Effects of L-arginine supplementation on biomarkers of glycemic control: a systematic review and meta-analysis of randomised clinical trials

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (3)

The present meta-analysis aimed to determine the effectiveness of L-arginine supplementation in improving biomarkers of glycemic control in adults. El......

Sex differences in the association between obesity and hypertension

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (3)

Background Hypertension and obesity often coexist. There are sex differences in the mechanisms of obesity-related hypertension but the reasons for the......

Nutraceutical management of metabolic syndrome as a palliative and a therapeutic to coronavirus disease (COVID) crisis

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (5)

The global market for medicinal plants and herbs is on the increase due to their desirability, efficacy, and less adverse effects as complementary and......

Exploring plant-based alpha-glucosidase inhibitors: promising contenders for combatting type-2 diabetes

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; ()

Objective: This systematic review aimed to provide comprehensive details on the & alpha;-G inhibitory potential of various bioactive compounds der......

Ellagic acid reduces hepatic lipid contents through regulation of SIRT1 and AMPK in old rats

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; ()

Objective: Ellagic acid is used in traditional medicine for the treatment of lipid disorders. In this study, the effects of ellagic acid on key regula......

Nesfatin-1 attenuates injury in a rat model of myocardial infarction by targeting autophagy, inflammation, and apoptosis

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (1)

Nesfatin-1 plays an important role in the modulation of heart performance. However, it remains unclear how nesfatin-1 contributes to cell survival in ......

Spermatogenesis and steroidogenesis disruption in a model of metabolic syndrome rats

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (1)

Context Metabolic syndrome (MetS) is a clustering of several physiological alterations. Objective This study was designed to evaluate the effects of M......

Ghrelin intronic lncRNAs,lnc-GHRL-3:2andlnc-GHRL-3:3, as novel biomarkers in type 2 diabetes mellitus

期刊: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 129 (1)

Background We aim to identify circulating lncRNAs located in the region of theghrelin(GHRL) gene that play a role in the development of T2DM. Methods ......

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