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In vitro models for ASD-patient-derived iPSCs and cerebral organoids

期刊: AUTISM, 2020; 173 ()

Autism spectrum disorder (ASD) is a set of pervasive neurodevelopmental disorders. The causation is multigenic in most cases, which makes it difficult......

Oxidative stress, metabolic and mitochondrial abnormalities associated with autism spectrum disorder

期刊: AUTISM, 2020; 173 ()

Autism spectrum disorder is a neurodevelopmental disorder characterized by impaired development and by abnormal function in regards to social interact......

The role of neuroglia in autism spectrum disorders

期刊: AUTISM, 2020; 173 ()

Neuroglia are a large class of neural cells of ectodermal (astroglia, oligodendroglia, and peripheral glial cells) and mesodermal (microglia) origin. ......

The early overgrowth theory of autism spectrum disorder: Insight into convergent mechanisms from valproic acid exposure and translational models

期刊: AUTISM, 2020; 173 ()

The development of new approaches for the clinical management of autism spectrum disorder (ASD) can only be realized through a better understanding of......

Microglia in animal models of autism spectrum disorders

期刊: AUTISM, 2020; 173 ()

Various genetic and environmental factors have been suggested to cause autism spectrum disorders (ASDs). A variety of animal models of ASDs have been ......

The role of the endocannabinoid system in autism spectrum disorders: Evidence from mouse studies

期刊: AUTISM, 2020; 173 ()

A substantive volume of research on autism spectrum disorder (ASD) has emerged in recent years adding to our understanding of the etiopathological pro......

Neurobiology of sensory processing in autism spectrum disorder

期刊: AUTISM, 2020; 173 ()

Altered sensory processing and perception has been one of the characteristics of autism spectrum disorder (ASD). In this chapter, we review the neural......

Resting-state abnormalities of posterior cingulate in autism spectrum disorder

期刊: AUTISM, 2020; 173 ()

The posterior cingulate cortex (PCC) plays pivotal roles in cognitive, social and emotional processing, as well as early neural development that suppo......

Autism spectrum disorder risk prediction: A systematic review of behavioral and neural investigations

期刊: AUTISM, 2020; 173 ()

A reliable diagnosis of autism spectrum disorder (ASD) is difficult to make until after toddlerhood. Detection in an earlier age enables early interve......

Genomics, transcriptomics, proteomics and big data analysis in the discovery of new diagnostic markers and targets for therapy development

期刊: AUTISM, 2020; 173 ()

Highly complex endophenotypes and underlying molecular mechanisms have prevented effective diagnosis and treatment of autism spectrum disorder. Despit......

The putative etiology and prevention of autism

期刊: AUTISM, 2020; 173 ()

Since the initial psychological report by Leo Kanner in 1943, relatively little formal biochemical/neurological research on the cause of autism, other......

The effects of oxytocin administration on individuals with ASD: Neuroimaging and behavioral evidence

期刊: AUTISM, 2020; 173 ()

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication and the presence of restricted i......

Role of environmental factors and epigenetics in autism spectrum disorders

期刊: AUTISM, 2020; 173 ()

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder thought to be caused by predisposing high-risk genes that may be altered during the ea......

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