期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 213 ()
Emerging evidence suggests an association of dysbiotic gut microbiota (GM) with atrial fibrillation (AF). The current study aimed to determine whether......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 213 ()
Cancer therapies have several clinical challenges associated with them, namely treatment toxicity, treatment resistance and relapse. Due to factors ra......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 213 ()
Neratinib (NE) is an irreversible pan-ERBB tyrosine kinase inhibitor used to treat breast cancers (BCa) with amplification of the ERBB2/HER2/Neu gene ......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 215 ()
Pseudomonas aeruginosa can utilize various virulence factors necessary for host infection and persistence. These virulence factors include pyocyanin, ......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 215 ()
Nucleotide-binding oligomerization domain (NOD)-like receptor type 2 protein (NLRP2) was reported to inhibit NF -KB in response to inflammatory stimul......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 215 ()
USP28 contributes to tumorigenesis through modulating the lifespan of oncogenic factors such as c-Myc and & UDelta;Np63, and it has been identifie......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 216 ()
Oral lichen planus (OLP) is a T cell-mediated autoimmune disease of oral mucosa concerning with the redox imbalance. Although glutamine uptake mediate......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 218 ()
Aldose reductase (AR) is an important enzyme involved in the reduction of various aldehyde and carbonyl compounds, including the highly reactive and t......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 208 ()
Heterotrimeric guanine nucleotide regulatory proteins (G-proteins) through the activation of several signaling mechanisms including adenylyl cyclase/c......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 209 ()
Immune checkpoints inhibition is a privileged approach to combat cancers and other human diseases. The TIM-3 (T cell immunoglobulin and mucin-domain c......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 212 ()
Acute myeloid leukemia (AML) is an aggressive malignancy of myeloid hematopoietic cells, which is characterized by the aberrant clonal proliferation o......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 212 ()
Osteoarthritis (OA) is an age-related joint disease with chronic inflammation, progressive articular cartilage destruction and subchondral bone sclero......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 213 ()
Aims: Abdominal aortic aneurysm (AAA) is a common, usually asymptomatic disease with high mortality and limited therapeutic options. Extensive extrace......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 214 ()
The dysregulation of Wnt/13-catenin signaling pathway is closely related to tumorigenesis, metastasis and cancer stem cell maintenance. Salinomycin is......
期刊: BIOCHEMICAL PHARMACOLOGY, 2023; 215 ()
An intricate interplay between genetic and environmental factors contributes to the development of type 2 diabetes (T2D) and its complications. Theref......