期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (5)
Human MPV17, an evolutionarily conserved mitochondrial inner-membrane channel protein, accounts for the tissue-specific mitochondrial DNA depletion sy......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (9)
Background: The Hindlimb unloaded mouse, an animal model of simulated microgravity demonstrates significant metabolic and hepatic derangements. Howeve......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (10)
Primary myelofibrosis (PM) is a myeloproliferative neoplasm characterized by stem cell-derived clonal neoplasms. Several factors are involved in diagn......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (12)
The activation loop (A-loop) of kinases, a key regulatory region, is recurrently mutated in several kinase proteins in cancer resulting in dysregulate......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (12)
In most microorganisms, cell division is guided by the divisome, a multiprotein complex that assembles at the equator of the cell and is responsible f......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (4)
Subclinical acute kidney injury (subAKI) is characterized by tubule-interstitial injury without significant changes in glomerular function. SubAKI is ......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (10)
Background: S1-like nucleases are widespread enzymes commonly used in biotechnology and molecular biology. Although it is commonly believed that they ......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (2)
Background: Protein Disulfide Isomerase (PDI) enzyme is an emerging therapeutic target in oncology and hematology. Although PDI reductase activity has......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (9)
Background: Pancreatic cancer is a deadly malignancy mainly because of its asymptomatic onset which prevents the implementation of the primary tumour'......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (9)
The remarkable structural diversity of glycans that is exposed at the cell surface and generated along the secretory pathway is tightly regulated by s......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (12)
Leptospira interrogans serovar Copenhageni's genome harbors two CRISPR-Cas systems belonging to subtypes I-B and I-C. However, in L. interrogans, the ......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (12)
Ramachandran (phi, psi) steric map was introduced in 1963 to describe available conformation space for protein structures. Subsequently, residues were......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (4)
Background: Identifying a biomarker for the decline in cognitive function in patients with diabetes is important. Therefore, we aimed to identify the ......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (6)
Background: Triple-negative breast cancer (TNBC) accounts for 20% of breast cancer that does not express HER2, progesterone and estrogen receptors. It......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2023; 1867 (10)
Dramatic advances in phosphoproteomics and the development of a selective chemical probe have presented new opportunities for revealing the cellular l......