期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundThe growing amount of high dimensional biomolecular data has spawned new statistical and computational models for risk prediction and diseas......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Background PacBio high fidelity (HiFi) sequencing reads are both long (15-20 kb) and highly accurate (> Q20). Because of these properties, they hav......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundThe field of epigenomics holds great promise in understanding and treating disease with advances in machine learning (ML) and artificial int......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Background: The growing power and ever decreasing cost of RNA sequencing (RNASeq) technologies have resulted in an explosion of RNA-Seq data productio......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundLiquid biopsy is a minimally-invasive method of sampling bodily fluids, capable of revealing evidence of cancer. The distribution of cell-fr......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Background: Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Background: Old mosquitoes are more likely to transmit malaria than young ones. Therefore, accurate prediction of mosquito population age can drastica......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundIt remains an important challenge to predict the functional consequences or clinical impacts of genetic variants in human diseases, such as ......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundConcurrent existence of lncRNA and circular RNA at both nucleus and cytosol within a cell at different proportions is well reported. Previou......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Deoxyribonucleic acid (DNA) is emerging as an alternative archival memory technology. Recent advancements in DNA synthesis and sequencing have both in......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundPan-genome graphs are gaining importance in the field of bioinformatics as data structures to represent and jointly analyze multiple genomes......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
Background: Subcellular localization of messenger RNA (mRNAs) plays a pivotal role in the regulation of gene expression, cell migration as well as in ......
期刊: BMC BIOINFORMATICS, 2023; 24 (1)
BackgroundBiologists are faced with an ever-changing array of complex software tools with steep learning curves, often run on High Performance Computi......