期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundAggregation of high-throughput biological data using pathway-based approaches is useful to associate molecular results to functional feature......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundGenome-scale models of metabolism and macromolecular expression (ME models) enable systems-level computation of proteome allocation coupled ......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundThe formation of acetate by fast-growing Escherichia coli (E. coli) is a commonly observed phenomenon, often referred to as overflow metabol......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundCells use signaling protein networks to sense their environment and mediate specific responses. Information about environmental stress is us......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundA recurrent problem in genome-scale metabolic models (GEMs) is to correctly represent lipids as biomass requirements, due to the numerous of......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundThe lack of a continuous long-term in vitro culture system for Plasmodium vivax severely limits our knowledge of pathophysiology of the most......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association ......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundThe Notch signaling pathway is involved in cell fate decision and developmental patterning in diverse organisms. A receptor molecule, Notch ......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundLiver has the unique ability to regenerate following injury, with a wide range of variability of the regenerative response across individual......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease, and it is a multifactorial disease with no definite diagnost......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
Background: There is little published regarding metabolism of Salinispora species. In continuation with efforts performed towards this goal, this stud......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundCholesterylester transfer protein (CETP) modulates the composition of various lipoproteins associated with cardiovascular disease. Despite i......
期刊： BMC SYSTEMS BIOLOGY, 2019; 13 ()
BackgroundUnderstanding what determines the between-host variability in infection dynamics is a key issue to better control the infection spread. In p......
