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Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss

期刊: CLIMACTERIC, 2023; ()

ObjectivesThis study aimed to analyze the role of estrogen in noise-induced hearing loss (NIHL) and uncover underlying mechanisms.MethodsAn ovariectom......

Quality of life in menopausal women in the workplace - a systematic review

期刊: CLIMACTERIC, 2023; 26 (2)

Menopausal women are a large and economically relevant group in the workforce. Yet their quality of life (QoL) and needs in the workplace have been ne......

Evaluation and management of endometriosis

期刊: CLIMACTERIC, 2023; 26 (3)

The initial diagnostic investigations for endometriosis are physical examination and pelvic ultrasound. The pelvic examination should include a specul......

Relationship between menopausal hormone therapy and incidence of fractures in postmenopausal women

期刊: CLIMACTERIC, 2023; ()

Objective: Long-term protective effects of menopausal hormone therapy (MHT) at fractures with different doses and components are controversial. We ana......

Optimizing sleep across the menopausal transition

期刊: CLIMACTERIC, 2023; 26 (3)

Women frequently experience sleep disturbances, particularly night-time awakenings, as they transition menopause and enter postmenopause. Sleep is ess......

Pharmacokinetics, safety and preliminary pharmacodynamic evaluation of DARE-VVA1: a soft gelatin capsule containing tamoxifen for the treatment of vulvovaginal atrophy

期刊: CLIMACTERIC, 2023; 26 (5)

Objective: This study aimed to measure safety, systemic pharmacokinetics and preliminary efficacy of a vaginal tamoxifen capsule (DARE-VVA1) among pos......

The impact of menopause education on quality of life among menopausal women: a systematic review with meta-analysis

期刊: CLIMACTERIC, 2023; 26 (5)

A systematic review with meta-analysis was conducted to establish the impact of menopause health education on quality of life (QoL) among menopausal w......

Impact of the new coronavirus (SARS-CoV-2) pandemic on climacteric women's health: Websurvey

期刊: CLIMACTERIC, 2023; 26 (6)

ObjectiveThe menopausal transition is an important milestone in female reproductive life. Many studies have been conducted to assess the impact of the......

The 2023 Practitioner's Toolkit for Managing Menopause

期刊: CLIMACTERIC, 2023; 26 (6)

ObjectiveThe Practitioner's Toolkit for Managing the Menopause, developed in 2014, provided an accessible desk-top tool for health-care practitioners ......

The effects of hormone replacement therapy on the microbiomes of postmenopausal women

期刊: CLIMACTERIC, 2023; 26 (3)

The sex steroid hormone estrogen plays a number of regulatory roles in female development. During menopause, estrogen synthesis in the ovaries decreas......

The role of microbiota in the management of genitourinary syndrome of menopause

期刊: CLIMACTERIC, 2023; 26 (4)

It is estimated that the 25-50% of women who are reaching menopause every year report symptoms related to the genitourinary syndrome of menopause (GSM......

Overexpression of miR-181a regulates the Warburg effect in triple-negative breast cancer

期刊: CLIMACTERIC, 2023; 26 (1)

ObjectiveTriple-negative breast cancer (TNBC) is highly aggressive and leads to a poor prognosis. microRNA-181a (miR-181a) exhibits strong antineoplas......

Effects of concurrent exercise on health-related quality of life in middle-aged women

期刊: CLIMACTERIC, 2023; 26 (2)

ObjectiveThis study aimed to evaluate the influence of a 16-week concurrent exercise program on health-related quality of life in middle-aged women.Me......

Genetic factors underlying insomnia and ovarian insufficiency

期刊: CLIMACTERIC, 2023; 26 (5)

Premature ovarian insufficiency (POI) is characterized by a loss of regular hormone production and egg release in women below the age of 40 years, whi......

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