Multiple sclerosis (MS) is a chronic autoimmune demyelinating and neurodegenerative disease of the central nervous system with a wide variety of clini......
Comorbidity between borderline personality disorder (BPD) and other mental disorders is common. Although no specific pharmacological treatments have b......
The sigma-1 receptor is a 223 amino acid-long protein with a recently identified structure. The sigma-2 receptor is a genetically unrelated protein wi......
IntroductionPhantom limb pain (PLP) refers to pain perceived in a part of the body removed by amputation or trauma. Despite the high prevalence of PLP......
Intravenous efgartigimod alfa (also known as efgartigimod alfa-fcab in the USA; Vyvgart (R)) is the first neonatal Fc receptor antagonist approved in ......
Background and Objectives Understanding the multi-faceted treatment outcomes of newly diagnosed epilepsy is critical for developing rational therapeut......
Rimegepant [Nurtec((R)) ODT (USA); Vydura((R)) (EU)] is a calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment ......
Gliomas are a heterogeneous group of brain tumors with limited therapeutic options. However, identification of BRAF V600E mutations in a subset of gli......
BackgroundConsidering the improvement in adherence and convenience, once-monthly paliperidone palmitate (PP1M) has been increasingly used in the treat......
Background Levetiracetam is widely used in post-stroke epilepsy. However, it is suspected to possess P-glycoprotein (P-gp) induction properties, and t......
BackgroundOnabotulinumtoxinA (BTX-A) and anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (anti-CGRP mAbs) are approved drugs for chr......
Background The question of whether multiple sclerosis requires life-long disease-modifying treatments (DMTs) remains unanswered. Some studies suggest ......
AimTo compare safety and functional outcomes of intravenous thrombolysis (IVT) between females and males with acute ischaemic stroke (AIS) in relation......
Background and Objective Status epilepticus in poststroke epilepsy is a challenging condition because of multiple vascular comorbidities and the advan......