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High Prevalence of a c.5979dupA Variant in the Dysferlin Gene (DYSF) in Individuals from a Semiarid Region of Brazil

期刊: CURRENT GENOMICS, 2023; 24 (5)

Background Dysferlinopathies represent a group of limb girdle or distal muscular dystrophies with an autosomal-recessive inheritance pattern resulting......

Identification of Plausible Candidates in Prostate Cancer Using Integrated Machine Learning Approaches

期刊: CURRENT GENOMICS, 2023; 24 (5)

Background Currently, prostate-specific antigen (PSA) is commonly used as a prostate cancer (PCa) biomarker. PSA is linked to some factors that freque......

Unraveling the Concealed Transcriptomic Landscape of PTEN in Human Malignancies

期刊: CURRENT GENOMICS, 2023; 24 (4)

Background Phosphatase and tensin homolog, widely known as PTEN, is a major negative regulator of the PI3K/AKT/mTOR signaling pathway, involved in the......

The Era of Plant Breeding: Conventional Breeding to Genomics-assisted Breeding for Crop Improvement

期刊: CURRENT GENOMICS, 2023; 24 (1)

Plant breeding has made a significant contribution to increasing agricultural production. Conventional breeding based on phenotypic selection is not e......

Insights into Metabolic Engineering of Bioactive Molecules in Tetrastigma hemsleyanum Diels & Gilg: A Traditional Medicinal Herb

期刊: CURRENT GENOMICS, 2023; 24 (2)

Plants are a vital source of bioactive molecules for various drug development processes. Tetrastigma hemsleyanum is one of the endangered medicinal pl......

Draft Genome Sequence of Enterobacter cloacae S23 a Plant Growth-promoting Passenger Endophytic Bacterium Isolated from Groundnut Nodule Possesses Stress Tolerance Traits

期刊: CURRENT GENOMICS, 2023; 24 (1)

Aim This study aims to reveal the passenger endophytic bacterium Enterobacter cloacae S23 isolated from groundnut nodules and to underpin the molecula......

Nonsynonymous Synonymous Variants Demand for a Paradigm Shift in Genetics

期刊: CURRENT GENOMICS, 2023; 24 (1)

Synonymous (also known as silent) variations are by definition not considered to change the coded protein. Still many variations in this category affe......

Identification of Potential Genes and Critical Pathways in Postoperative Recurrence of Crohn's Disease by Machine Learning And WGCNA Network Analysis

期刊: CURRENT GENOMICS, 2023; 24 (2)

Background: Crohn's disease (CD) is a chronic idiopathic inflammatory bowel disease affecting the entire gastrointestinal tract from the mouth to the ......

Epigenetic Diversity Underlying Seasonal and Annual Variations in Brown Planthopper (BPH) Populations as Revealed by Methylation- sensitive Restriction Assay

期刊: CURRENT GENOMICS, 2023; 24 (6)

Background: The brown planthopper (BPH) is a monophagous sap-sucking insect pest of rice that is responsible for massive yield loss. BPH populations, ......

Using Chaos-Game-Representation for Analysing the SARS-CoV-2 Lineages, Newly Emerging Strains and Recombinants

期刊: CURRENT GENOMICS, 2023; 24 (3)

Background Viruses have high mutation rates, facilitating rapid evolution and the emergence of new species, subspecies, strains and recombinant forms.......

Modulation of Plant MicroRNA Expression: Its Potential Usability in Wheat (Triticum aestivum L.) Improvement

期刊: CURRENT GENOMICS, 2023; 24 (4)

Wheat, a crucial crop for the pursuit of food security, is faced with a plateauing yield projected to fall short of meeting the demands of the exponen......

Oxford Nanopore Technology and its Application in Liquid Biopsies

期刊: CURRENT GENOMICS, 2023; 24 (6)

Advanced medical technologies are transforming the future of healthcare, in particular, the screening and detection of molecular-genetic changes in pa......

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