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Notch signaling regulates neural stem cell quiescence entry and exit in Drosophila

期刊: DEVELOPMENT, 2022; 149 (4)

Stem cells enter and exit quiescence as part of normal developmental programs and to maintain tissue homeostasis in adulthood. Although it is clear th......

JIF:4.841

Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium

期刊: DEVELOPMENT, 2022; 149 (6)

During development, the heart grows by addition of progenitor cells to the poles of the primordial heart tube. In the zebrafish, Wilms tumor 1 transcr......

JIF:4.841

Natural killer cells act as an extrinsic barrier for in vivo reprogramming

期刊: DEVELOPMENT, 2022; 149 (8)

The ectopic expression of the transcription factors OCT4, SOX2. KLF4 and MYC (OSKM) enables reprogramming of differentiated cells into pluripotent emb......

JIF:4.841

Microglia in brain development and regeneration

期刊: DEVELOPMENT, 2022; 149 (8)

It has recently emerged that microglia, the tissue-resident macrophages of the central nervous system, play significant noninnate immune roles to supp......

JIF:4.841

Regenerative neurogenesis: the integration of developmental physiological and immune signals

期刊: DEVELOPMENT, 2022; 149 (8)

In fishes and salamanders, but not mammals, neural stem cells switch back to neurogenesis after injury. The signalling environment of neural stem cell......

JIF:4.841

The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development

期刊: DEVELOPMENT, 2022; 149 (9)

In central nervous system vascular endothelial cells, signaling via the partially redundant ligands WNT7A and WNT7B requires two co-activator proteins......

JIF:4.841

Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2

期刊: DEVELOPMENT, 2022; 149 (9)

The endocardium plays important roles in the development and function of the vertebrate heart; however, few molecular markers of this tissue have been......

JIF:4.841

The regenerative capacity of neonatal tissues

期刊: DEVELOPMENT, 2022; 149 (12)

It is well established that humans and other mammals are minimally regenerative compared with organisms such as zebrafish, salamander or amphibians. I......

JIF:4.841

Foxl2 is required for the initiation of the female pathway in a temperature-dependent sex determination system in Trachemys scripta

期刊: DEVELOPMENT, 2022; 149 (13)

KDM6B-mediated epigenetic modification of the testicular regulator Dmrtl has previously been identified as the primary switch of the male pathway in a......

JIF:4.841

Breasi-CRISPR: an efficient genome-editing method to interrogate protein localization and protein-protein interactions in the embryonic mouse cortex

期刊: DEVELOPMENT, 2022; 149 (18)

In developing tissues, knowing the localization and interactors of proteins of interest is key to understanding their function. Here, we describe the ......

JIF:4.841

Human neural progenitors establish a diffusion barrier in the endoplasmic reticulum membrane during cell division

期刊: DEVELOPMENT, 2022; 149 (20)

Asymmetric segregation of cellular components regulates the fate and behavior of somatic stem cells. Similar to dividing budding yeast and precursor c......

JIF:4.841

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