期刊: DEVELOPMENT, 2022; 149 (4)
Stem cells enter and exit quiescence as part of normal developmental programs and to maintain tissue homeostasis in adulthood. Although it is clear th......
期刊: DEVELOPMENT, 2022; 149 (6)
During development, the heart grows by addition of progenitor cells to the poles of the primordial heart tube. In the zebrafish, Wilms tumor 1 transcr......
期刊: DEVELOPMENT, 2022; 149 (8)
The ectopic expression of the transcription factors OCT4, SOX2. KLF4 and MYC (OSKM) enables reprogramming of differentiated cells into pluripotent emb......
期刊: DEVELOPMENT, 2022; 149 (8)
It has recently emerged that microglia, the tissue-resident macrophages of the central nervous system, play significant noninnate immune roles to supp......
期刊: DEVELOPMENT, 2022; 149 (8)
In fishes and salamanders, but not mammals, neural stem cells switch back to neurogenesis after injury. The signalling environment of neural stem cell......
期刊: DEVELOPMENT, 2022; 149 (9)
In central nervous system vascular endothelial cells, signaling via the partially redundant ligands WNT7A and WNT7B requires two co-activator proteins......
期刊: DEVELOPMENT, 2022; 149 (9)
The endocardium plays important roles in the development and function of the vertebrate heart; however, few molecular markers of this tissue have been......
期刊: DEVELOPMENT, 2022; 149 (12)
It is well established that humans and other mammals are minimally regenerative compared with organisms such as zebrafish, salamander or amphibians. I......
期刊: DEVELOPMENT, 2022; 149 (13)
KDM6B-mediated epigenetic modification of the testicular regulator Dmrtl has previously been identified as the primary switch of the male pathway in a......
期刊: DEVELOPMENT, 2022; 149 (18)
In developing tissues, knowing the localization and interactors of proteins of interest is key to understanding their function. Here, we describe the ......
期刊: DEVELOPMENT, 2022; 149 (20)
Asymmetric segregation of cellular components regulates the fate and behavior of somatic stem cells. Similar to dividing budding yeast and precursor c......